851028-69-8

Basic information

• Product Name: 1-Pyrrolidinecarboxylic acid, 2-[[5-(1-methylcyclohexyl)-1,3,4-oxadiazol-2-yl]carbonyl]-, 1,1-dimethylethyl ester, (2S)-
• CAS NO: 851028-69-8
• Molecular Formula: C19H29N3O4
• Molecular Weight: 363.457
• Mol File: 851028-69-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-Pyrrolidinecarboxylic acid, 2-[[5-(1-methylcyclohexyl)-1,3,4-oxadiazol-2-yl]carbonyl]-, 1,1-dimethylethyl ester, (2S)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Pyrrolidinecarboxylic acid, 2-[[5-(1-methylcyclohexyl)-1,3,4-oxadiazol-2-yl]carbonyl]-, 1,1-dimethylethyl ester, (2S)-(851028-69-8)
• EPA Substance Registry System: 1-Pyrrolidinecarboxylic acid, 2-[[5-(1-methylcyclohexyl)-1,3,4-oxadiazol-2-yl]carbonyl]-, 1,1-dimethylethyl ester, (2S)-(851028-69-8)

Safety Data

• Hazardous Substances Data: 851028-69-8(Hazardous Substances Data)

Upstream product

• 115186-37-3 tert-butyl (2S)-2-{[N-methoxy(N-methyl)amino]carbonyl}pyrrolidine-1-carboxylate 
• 15761-39-4 1-(tert-butoxycarbonyl)-L-proline 
• 59936-29-7 (S)-N-(tert-butoxycarbonyl)proline methyl ester 

Relevant articles and documents

Synthesis, SAR, and X-ray structure of novel potent DPPIV inhibitors: Oxadiazolyl ketones

Synthesis of a novel series of DPPIV inhibitors with 1,2,4- and 1,3,4-oxadiazolyl ketone derivatives and its structure-activity relationships are discussed. Compound 18h showed good inhibitory activity against DPPIV and favorable pharmacokinetic properties. In vivo pharmacodynamic efficacy and co-crystal structure of compound 18h with DPPIV is also described.