85108-59-4Relevant articles and documents
Design and synthesis of novel quinoxaline derivatives as potential candidates for treatment of multidrug-resistant and latent tuberculosis
Santiva?ez-Veliz, Mery,Pérez-Silanes, Silvia,Torres, Enrique,Moreno-Viguri, Elsa
, p. 2188 - 2193 (2016)
Twenty-four quinoxaline derivatives were evaluated for their antimycobacterial activity using BacTiter-Glo microbial cell viability assay. Five compounds showed MIC values 50 values 1.5 μM in primary screening and therefore, they
2-(3-Aryl-2-propenoyl)-3-methylquinoxaline-1,4-dioxides: A novel cluster of tumor-specific cytotoxins which reverse multidrug resistance
Das, Umashankar,Pati, Hari N.,Panda, Atulya K.,Clercq, Erik De,Balzarini, Jan,Molnar, Joseph,Barath, Zoltan,Ocsovszki, Imre,Kawase, Masami,Zhou, Li,Sakagami, Hiroshi,Dimmock, Jonathan R.
experimental part, p. 3909 - 3915 (2009/10/02)
A series of 2-(3-aryl-2-propenoyl)-3-methylquinoxaline-1,4-dioxides 3a-l were prepared by condensation of various aryl aldehydes with 2-acetyl-3-methylquinoxaline-1,4-dioxide 2. These compounds inhibit the growth of human Molt 4/C8 and CEM T-lymphocytes a
A new Route for the Synthesis of Phenazine Di-N-Oxides
El-Halim, M. S. Abd,El-Ahl, A. S.,Etman, H. A.,Ali, M. M.,Fouda, A.,Fadda, A. A.
, p. 1217 - 1224 (2007/10/03)
Several phenazine 5,10-dioxides (7a-d) were prepared by the reaction of 2-methyl-3-acetylquinoxaline 1,4-dioxide (2) with different aromatic aldehydes or by direct cyclization of the quinoxaline cinnamoyl derivatives 3 in basic medium.In addition, the phe
