85120-75-8

Basic information

• Product Name: (R)-(+)-4-(4'-acetoxyphenyl)-2-butyl acetate
• Synonyms: (R)-(+)-4-(4'-acetoxyphenyl)-2-butyl acetate
• CAS NO: 85120-75-8
• Molecular Weight: 250.295
• Mol File: 85120-75-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (R)-(+)-4-(4'-acetoxyphenyl)-2-butyl acetate(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-(+)-4-(4'-acetoxyphenyl)-2-butyl acetate(85120-75-8)
• EPA Substance Registry System: (R)-(+)-4-(4'-acetoxyphenyl)-2-butyl acetate(85120-75-8)

Safety Data

• Hazardous Substances Data: 85120-75-8(Hazardous Substances Data)

Upstream product

• 108-05-4 vinyl acetate 
• 69617-84-1 rac-rhododendrol 
• 5471-51-2 4-(4-hydroxyphenyl)-2-oxobutane 

Downstream Products

• 129752-69-8 (R)-(+)-4-(4'-hydroxyphenyl)-2-butyl acetate 
• 59092-94-3 (R)-rhododendrol 

Relevant articles and documents

Asymmetric synthesis of enantiomerically pure zingerols by lipase-catalyzed transesterification and efficient synthesis of their analogues

The achiral zingerone 1, readily available from ginger, can be easily transformed into chiral derivatives. Zingerol 2, a reduced product of zingerone 1 is expected to be an important new medicinal lead compound. We have achieved a concise synthesis of optically active zingerol (R)-2 and (S)-2 by the lipase-catalyzed stereoselective transesterification of racemic 2. Under the optimized conditions, a lipase from Alcaligenes sp. (Meito QLM) and vinyl acetate in i-Pr2O or hexane at 35 C within 1 h gave the alcohol (S)-2 and the acetate (R)-9 with high enantioselectivity without producing acetylated by-products. Since optically active (S)-2 and (R)-9 were obtained through lipase-catalyzed transesterification, other enantiomerically pure novel compounds could all be synthesized.