851228-80-3

Basic information

• Product Name: C₃₈H₆₉NO₃Si₂
• Synonyms: C₃₈H₆₉NO₃Si₂
• CAS NO: 851228-80-3
• Molecular Weight: 644.142
• Mol File: 851228-80-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: C₃₈H₆₉NO₃Si₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₃₈H₆₉NO₃Si₂(851228-80-3)
• EPA Substance Registry System: C₃₈H₆₉NO₃Si₂(851228-80-3)

Safety Data

• Hazardous Substances Data: 851228-80-3(Hazardous Substances Data)

Upstream product

• 5080-22-8 N-isopropylhydroxyamine 
• 143884-26-8 (5Z,7E,20R)-1α,3β-bis<(tert-butyldimethylsilyl)oxy>-20-formylmethyl-9,10-seco-5,7,10(19)-pregnatriene 
• 151919-93-6 (5Z,7E,20R)-1α,3β-bis(tert-butyldimethylsilyloxy)-20-cyanomethyl-9,10-seco-5,7,10(19)-pregnatriene 
• 114694-12-1 (5Z,7E)-(1S,3R,20S)-1,3-bis<(tert-butyldimethylsilyl)oxy>-9,10-seco-22,23-dinor-5,7,10(19)-cholatrien-24-ol 
• 114694-13-2 (5Z,7E)-(1S,3R,20S)-1,3-bis<(tert-butyldimethylsilyl)oxy>-9,10-seco-22,23-dinor-5,7,10(19)-cholatrienol 22-p-toluenesulfonate 
• 50632-53-6 N-isopropylhydroxylamine hydrochloride 

Downstream Products

• 851228-81-4 3-((R)-2-{(1R,3aS,7aR)-4-[2-[(3S,5R)-3,5-Bis-(tert-butyl-dimethyl-silanyloxy)-2-methylene-cyclohex-(Z)-ylidene]-eth-(E)-ylidene]-7a-methyl-octahydro-inden-1-yl}-propyl)-2-isopropyl-5-methyl-isoxazolidine-5-carboxylic acid methyl ester 

Relevant articles and documents

Practical synthesis and evaluation of the biological activities of 1α,25-dihydroxyvitamin D3 antagonists, 1α,25- dihydroxyvitamin D3-26,23-lactams. Designed on the basis of the helix 12-folding inhibition hypothesis

A practical synthetic route to novel vitamin D antagonists of DLAM (1α,25-dihydroxyvitamin D3-26,23-lactam) was developed from vitamin D2 via the 1,3-dipolar cycloaddition reaction as a key step. Six DLAM derivatives (24 compounds) w