85222-33-9

Basic information

• Product Name: 6-(6,7-Dimethoxy-2-methyl-1,2,3,4-tetrahydro-isoquinolin-1-ylmethyl)-2,3-dimethoxy-benzoic acid methyl ester
• Synonyms: 6-(6,7-Dimethoxy-2-methyl-1,2,3,4-tetrahydro-isoquinolin-1-ylmethyl)-2,3-dimethoxy-benzoic acid methyl ester
• CAS NO: 85222-33-9
• Molecular Weight: 415.486
• Mol File: 85222-33-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 6-(6,7-Dimethoxy-2-methyl-1,2,3,4-tetrahydro-isoquinolin-1-ylmethyl)-2,3-dimethoxy-benzoic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 6-(6,7-Dimethoxy-2-methyl-1,2,3,4-tetrahydro-isoquinolin-1-ylmethyl)-2,3-dimethoxy-benzoic acid methyl ester(85222-33-9)
• EPA Substance Registry System: 6-(6,7-Dimethoxy-2-methyl-1,2,3,4-tetrahydro-isoquinolin-1-ylmethyl)-2,3-dimethoxy-benzoic acid methyl ester(85222-33-9)

Safety Data

• Hazardous Substances Data: 85222-33-9(Hazardous Substances Data)

Upstream product

• 30045-07-9 2-methyl-6,7-dimethoxy-3,4-dihydroisoquinolinium iodide 
• 76177-36-1 Methyl α-bromo-5,6-dimethoxy-o-toluate 

Relevant articles and documents

Novel Zinc-Promoted Alkylation of Iminium Salts. New Synthesis of Benzylisoquinoline, Phthalidylisoquinoline, and Protoberberine Alkaloids and Related Compounds

Zinc-promoted reductive coupling reaction of iminium salts with alkyl halides was found to be a successful key reaction for synthesis of a variety of alkaloids such as benzylisoquinoline, phthalidylisoquinoline, and protoberberine alkaloids.More specifically, laudanosine, cordrastine, hydrastine, narcotine, tetrahydropalmatine, and canadine were obtained.A new route for the synthesis of the emetine and yohimbine skeletons was exploited.