85223-10-5Relevant articles and documents
HIGHLY EFFICIENT METHOD FOR PRODUCING SATURATED HOMOETHER FROM UNSATURATED CARBONYL COMPOUND
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Paragraph 0049; 0051-0052, (2020/07/16)
PROBLEM TO BE SOLVED: To provide a method for efficiently producing a saturated homoether from an unsaturated carbonyl compound. SOLUTION: The method for producing an unsaturated homoether uses an unsaturated carbonyl compound and hydrogen as a raw material, uses a catalyst comprising a metal supported on an acidic catalyst carrier and performs at least once a pressure reduction operation so that a differential pressure from a reaction pressure is 0.01 MPa or more. In the method, the metal of the catalyst is, for example, palladium and the carrier of the catalyst is alumina, silica, silica-alumina or the like. The unsaturated carbonyl compound serving as a raw material is 2-butenal, 2-ethyl-2-hexenal, 2-ethyl-2-butenal, 2-hexenal or the like and the produced saturated homoether is dibutyl ether, bis(2-ethylhexyl)ether, bis(2-ethylbutyl)ether, dihexyl ether or the like. SELECTED DRAWING: None COPYRIGHT: (C)2020,JPOandINPIT
Utilization of hexabromoacetone for protection of alcohols and aldehydes and deprotection of acetals, ketals, and oximes under UV irradiation
Chaiseeda, Kittichai,Chantharadet, Ladawan,Chavasiri, Warinthorn
, p. 1305 - 1323 (2017/10/30)
Hexabromoacetone (HBA) was efficiently used for the protection of alcohols and aldehydes and deprotection of benzaldehyde dimethyl acetal, solketal, and other acetals and ketals. In only 10?min, the protection of glycerol yielded 90% of solketal and protection of benzaldehyde gave 95% of benzaldehyde dimethyl acetal. The deprotection of benzaldehyde dimethyl acetal under UV irradiation gave over 90% yield of benzaldehyde within 15?s using only 2.5?mol% of HBA. HBA was also successfully used for deoximation. Solvent was found to play an important role in the efficiency of HBA for these reactions.
Preparation method of key intermediate 2-ethyl butyraldehyde of 2-ethyl butyric acid
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Paragraph 0011-0012, (2017/07/19)
The invention provides a preparation method of a key intermediate, 2-ethyl butyraldehyde, of 2-ethyl butyric acid, wherein the preparation method includes the steps of: adding an ethyl magnesium halide Grignard reagent to a protected alpha-halogenated aldehyde (I) solution, and performing a stirring reaction for 1-10 h at a certain temperature; performing post-treatment and de-protecting the product to obtain the 2-ethyl butyraldehyde. A route in the process in represented as follows. The method has short route and high usage ratio, is low in cost and easy to industrialize, and avoids defects in conventional methods.