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852331-49-8

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  • Boronic acid,B-[(2R)-1-[2-[(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)amino]acetyl]-2-pyrrolidinyl]-

    Cas No: 852331-49-8

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852331-49-8 Usage

Description

Vildagliptin-Boronic Acid is a chemical compound that functions as an inhibitor of dipeptidyl peptidase-4 (DPP-4), an enzyme that plays a key role in the regulation of blood glucose levels. It is derived from Vildagliptin, a medication commonly used for treating type 2 diabetes, with the addition of boronic acid to enhance its inhibitory activity. Vildagliptin-Boronic Acid works by blocking DPP-4, leading to increased levels of glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP), which are crucial in managing insulin secretion and blood sugar levels. The incorporation of boronic acid significantly boosts the potency of Vildagliptin-Boronic Acid, making it a viable option for patients struggling to control their blood sugar levels through diet and exercise alone.

Uses

Used in Pharmaceutical Industry:
Vildagliptin-Boronic Acid is used as an antidiabetic medication for the treatment of type 2 diabetes. It is particularly beneficial for patients who cannot effectively manage their blood sugar levels through diet and exercise alone. Vildagliptin-Boronic Acid serves to increase the levels of GLP-1 and GIP, which are instrumental in regulating insulin secretion and maintaining healthy blood sugar levels.
Used in Enhancing Medication Potency:
In the development of pharmaceuticals, Vildagliptin-Boronic Acid is used as a means to enhance the inhibitory activity of Vildagliptin. The addition of boronic acid to the compound amplifies its effectiveness in blocking the DPP-4 enzyme, thereby providing a more potent treatment option for diabetes management.
Used in Research and Development:
Vildagliptin-Boronic Acid is also utilized in scientific research and development for exploring new avenues in diabetes treatment. Its unique properties and enhanced potency make it a valuable subject for studies aimed at understanding and improving the management of type 2 diabetes and related metabolic disorders.

Check Digit Verification of cas no

The CAS Registry Mumber 852331-49-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,5,2,3,3 and 1 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 852331-49:
(8*8)+(7*5)+(6*2)+(5*3)+(4*3)+(3*1)+(2*4)+(1*9)=158
158 % 10 = 8
So 852331-49-8 is a valid CAS Registry Number.
InChI:InChI=1/C16H27BN2O4/c20-14(19-3-1-2-13(19)17(22)23)9-18-15-5-11-4-12(6-15)8-16(21,7-11)10-15/h11-13,18,21-23H,1-10H2/t11?,12?,13-,15?,16?/m0/s1

852331-49-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name [(2R)-1-[2-[(3-hydroxy-1-adamantyl)amino]acetyl]pyrrolidin-2-yl]boronic acid

1.2 Other means of identification

Product number -
Other names Vildagliptinboronic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:852331-49-8 SDS

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