852469-75-1Relevant articles and documents
COMPOUNDS AS NEUROKININ-1 RECEPTOR ANTAGONISTS AND USES THEREOF
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Page/Page column 42-43, (2020/02/16)
The present invention relates compounds of Formula (A) as NK-1 receptor antagonists, as well as their preparation and uses, and further relates pharmaceutical compositions comprising these compounds and their uses as modulators of dysfunctional glutamate
UREA DERIVATIVE AND USE THEREFOR
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Paragraph 0208; 0209, (2018/07/29)
The purpose of the present invention is to provide a compound with inhibitory activity on Discoidin Domain Receptor 1. The present invention provides a urea derivative represented by the formula (I) below or a pharmaceutically acceptable salt thereof.
Pentafluorosulfanyl-Substituted Benzopyran Analogues As New Cyclooxygenase-2 Inhibitors with Excellent Pharmacokinetics and Efficacy in Blocking Inflammation
Zhang, Yanmei,Wang, Yican,He, Chuang,Liu, Xiaorong,Lu, Yongzhi,Chen, Tingting,Pan, Qiong,Xiong, Jingfang,She, Miaoqin,Tu, Zhengchao,Qin, Xiaochu,Li, Minke,Tortorella, Micky D.,Talley, John J.
, p. 4135 - 4146 (2017/06/05)
In this report, we disclose the design and synthesis of a series of pentafluorosulfanyl (SF5) benzopyran derivatives as novel COX-2 inhibitors with improved pharmacokinetic and pharmacodynamic properties. The pentafluorosulfanyl compounds showe