85248-86-8 Usage
Description
(±)-N,N-dimethyl-5-oxopyrrolidine-2-carboxamide is a pyrrolidine derivative with a molecular formula of C7H12N2O2. It features a ketone group and a carboxamide functional group, making it a versatile building block in organic synthesis and pharmaceutical research.
Uses
Used in Pharmaceutical Research:
(±)-N,N-dimethyl-5-oxopyrrolidine-2-carboxamide is used as a building block for the development of new pharmaceutical compounds due to its unique structure and properties. Its potential biological activities and therapeutic effects make it a valuable candidate for medicinal chemistry.
Used in Organic Synthesis:
(±)-N,N-dimethyl-5-oxopyrrolidine-2-carboxamide is used as a key intermediate in the synthesis of various organic compounds, contributing to the creation of a wide range of chemical products across different industries.
Check Digit Verification of cas no
The CAS Registry Mumber 85248-86-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,5,2,4 and 8 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 85248-86:
(7*8)+(6*5)+(5*2)+(4*4)+(3*8)+(2*8)+(1*6)=158
158 % 10 = 8
So 85248-86-8 is a valid CAS Registry Number.
85248-86-8Relevant articles and documents
Impact of Functional Groups on the Copper-Initiated N-Arylation of 5-Functionalized Pyrrolidin-2-ones and Their Vinylogues
Baudelet, Davy,Da?ch, Adam,Rigo, Beno?t,Lipka, Emmanuelle,Gautret, Philippe,Homerin, Germain,Claverie, Christelle,Rousseau, Jolanta,Abuhaie, Cristina-Maria,Ghinet, Alina
, p. 2226 - 2244 (2016/07/15)
The electronic effects governing the N-arylation of pyrrolidone were investigated. The generalization of our preliminary findings on a copper(I)-catalyzed Csp2-N coupling process was first improved with a wide variety of aryl and heteroaryl halides and methyl pyroglutamate. The optimized protocol was further extended to pyrrolidin-2-ones substituted at the C5-position with an aryl group bearing an electron-donating or electron-withdrawing group as well as to some of their substituted enaminoester vinylogues. The impact of substituents at the N- and C5-position on these coupling processes seemed to be pivotal for determining both the reaction profiles and yields.