85267-92-1

Basic information

• Product Name: 2,3-diphenyl-4-methyl-1-penten-3-ol
• Synonyms: 2,3-diphenyl-4-methyl-1-penten-3-ol
• CAS NO: 85267-92-1
• Molecular Weight: 252.356
• Mol File: 85267-92-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2,3-diphenyl-4-methyl-1-penten-3-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-diphenyl-4-methyl-1-penten-3-ol(85267-92-1)
• EPA Substance Registry System: 2,3-diphenyl-4-methyl-1-penten-3-ol(85267-92-1)

Safety Data

• Hazardous Substances Data: 85267-92-1(Hazardous Substances Data)

Upstream product

• 98-81-7 1-bromovinylbenzene 
• 611-70-1 phenyl isopropyl ketone 
• 4452-11-3 1,2-diphenylprop-2-en-1-one 
• 1888-75-1 isopropyllithium 

Downstream Products

• 85267-80-7 (4-methylpenta-1,3-diene-2,3-diyl)dibenzene 

Relevant articles and documents

Copper-catalyzed cyanomethylation of allylic alcohols with concomitant 1,2-aryl migration: Efficient synthesis of functionalized ketones containing an α-quaternary center

A copper-catalyzed alkylation of allylic alcohols by alkyl nitriles with concomitant 1,2-aryl migration was developed. Formation of the alkyl nitrile radical was followed by its intermolecular addition to alkenes and the migration of a vicinal aryl group with the concomitant generation of a carbonyl functionality to complete the domino sequence. Mechanistic studies suggested that 1,2-aryl migration proceeded through a radical pathway (neophyl rearrangement). The protocol provided an efficient route to functionalized ketones containing an α-quaternary center.