853065-18-6

Basic information

• Product Name: C₃₁H₅₀N₂O₅Si
• Synonyms: C₃₁H₅₀N₂O₅Si
• CAS NO: 853065-18-6
• Molecular Weight: 558.834
• Mol File: 853065-18-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₃₁H₅₀N₂O₅Si(CAS DataBase Reference)
• NIST Chemistry Reference: C₃₁H₅₀N₂O₅Si(853065-18-6)
• EPA Substance Registry System: C₃₁H₅₀N₂O₅Si(853065-18-6)

Safety Data

• Hazardous Substances Data: 853065-18-6(Hazardous Substances Data)

Upstream product

• 160744-60-5 4-((tert-butyldimethylsilyloxy)methyl)benzaldehyde 
• 20605-01-0 diethyl bis(hydroxymethyl)malonate 
• 853065-13-1 2-[4-(tert-butyl-dimethyl-silanyloxymethyl)-phenyl]-[1,3]dioxane-5,5-dicarboxylic acid bis-[(1-hydroxymethyl-2,2-dimethyl-propyl)-amide] 
• 853065-09-5 2-[4-(tert-butyl-dimethyl-silanyloxymethyl)-phenyl]-[1,3]dioxane-5,5-dicarboxylic acid diethyl ester 

Relevant articles and documents

2-Aryl-5,5-bisoxazolin-2-yl[1,3]dioxanes as solution phase and immobilised ligands for highly enantioselective cyclopropanations

2-Aryl-5,5-bisoxazolin-2-yl[1,3]dioxanes 5, which can be easily prepared in three steps from diethyl bishydroxymethylmalonate, amino alcohol and an aromatic aldehyde, have been used for the copper catalysed asymmetric cyclopropanation of styrene with ethyl diazoacetate in up to 99% ee for the trans-cyclopropane. Grafting onto a bromo-Wang resin produced an immobilised ligand 9 which gave the trans-cyclopropane in 65% ee.