85312-59-0

Basic information

• Product Name: trans-4'(4-n-Propylcyclohexyl)-3,4-difluor-1,1'-biphenyl(bch-3f.f)
• Synonyms: trans-4'(4-n-Propylcyclohexyl)-3,4-difluor-1,1'-biphenyl(bch-3f.f);4''-(TRANS-4-PROPYLCYCLOHEXYL)-3,4-DIFLUOROBIPHENYL;3,4-Difluoro-4`-(4-propyl-cyclohexyl)biphenyl;trans-3,4-Difluoro-4'-(4-n-propylcyclohexyl)biphenyl, 97%;3,4-Difluoro-4'-(trans-4-propylcyclohexyl)biphenyl;trans-4'(4-n-Propylcyclohexyl)-3,4-difluor-1,1‘-biphenyl;3,4-Difluoro-4'-((trans-4-propylcyclohexyl)-1,1'-biphenyl;3,4-Difluoro-4'-((trans-4-propylcyclohexyl)
• CAS NO: 85312-59-0
• Molecular Formula: C21H24F2
• Molecular Weight: 314.417
• Mol File: 85312-59-0.mol
• Article Data: 5

Chemical Properties

• Melting Point: 66-68℃
• Boiling Point: 404 ºC at 760 mmHg
• Flash Point: 167.6ºC
• Appearance: /
• Density: N/0A
• Storage Temp.: Sealed in dry,Room Temperature
• Water Solubility: Sparingly soluble in water.
• CAS DataBase Reference: trans-4'(4-n-Propylcyclohexyl)-3,4-difluor-1,1'-biphenyl(bch-3f.f)(CAS DataBase Reference)
• NIST Chemistry Reference: trans-4'(4-n-Propylcyclohexyl)-3,4-difluor-1,1'-biphenyl(bch-3f.f)(85312-59-0)
• EPA Substance Registry System: trans-4'(4-n-Propylcyclohexyl)-3,4-difluor-1,1'-biphenyl(bch-3f.f)(85312-59-0)

Safety Data

• Hazardous Substances Data: 85312-59-0(Hazardous Substances Data)

Usage

Chemical Properties

White crystalline powder

Upstream product

• 696-02-6 4-chloro-1,2-difluorobenzene 
• 182169-61-5 Dichloro-ethyl-[4-(4-propyl-cyclohexyl)-phenyl]-silane 
• 348-61-8 1-bromo-3,4-difluorobenzene 
• 184705-98-4 4-(trans-4-n-Propylcyclohexyl)phenyltrimethoxysilane 
• 86579-53-5 1-(trans-4-n-propylcyclohexyl)-4-bromobenzene 
• 168267-41-2 (3,4-difluorophenyl)boronic acid 

Relevant articles and documents

The Hiyama Cross-Coupling Reaction at Parts Per Million Levels of Pd: In Situ Formation of Highly Active Spirosilicates in Glycol Solvents

A palladium NNC-pincer complex at a 5 mol ppm loading efficiently catalyzed the Hiyama coupling reaction of aryl bromides with aryl(trialkoxy)silanes in propylene glycol to give the corresponding biaryls in excellent yields. This method was applied to the syntheses of adapalene and a biaryl-type liquid-crystalline compound, as well as to the derivatization of dextromethorphan and norfloxacin. ESI-MS and NMR analyses of the reaction mixture suggested the formation of pentacoordinate spirosilicate intermediates in situ. Preliminary theoretical studies revealed that the glycol-derived silicate intermediates formed in situ are quite reactive silicon reagents in the transmetalation step.

NaOH-Promoted cross-coupling reactions of organosilicon compounds with organic halides: Practical routes to biaryls, alkenylarenes and conjugated dienes

The use of NaOH has been found to extremely effective in promoting the palladium-catalyzed cross-coupling reactions of aryl and alkenylchlorosilanes with organic halides such as aryl bromides and chlorides under very mild conditions.

Cross-coupling reactions of aryl chlorides with organochlorosilanes: Highly effective methods for arylation or alkenylation of aryl chlorides

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