853687-38-4

Basic information

• Product Name: 5,7,3’,4’-O-tetra-tert-butyldimethylsilylepicatechin
• Synonyms: 5,7,3’,4’-O-tetra-tert-butyldimethylsilylepicatechin
• CAS NO: 853687-38-4
• Molecular Weight: 747.323
• Mol File: 853687-38-4.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 5,7,3’,4’-O-tetra-tert-butyldimethylsilylepicatechin(CAS DataBase Reference)
• NIST Chemistry Reference: 5,7,3’,4’-O-tetra-tert-butyldimethylsilylepicatechin(853687-38-4)
• EPA Substance Registry System: 5,7,3’,4’-O-tetra-tert-butyldimethylsilylepicatechin(853687-38-4)

Safety Data

• Hazardous Substances Data: 853687-38-4(Hazardous Substances Data)

Upstream product

• 16198-01-9 (-)-epicatechin pentaacetate 
• 490-46-0 (2R,3R)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-1[2H]-benzopyran-3,5,7-triol 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 853687-37-3 (-)-ECG-7TBS 

Downstream Products

• 853687-43-1 2-[3,4-bis-(tert-butyl-dimethyl-silanyloxy)-phenyl]-5,7-bis-(tert-butyl-dimethyl-silanyloxy)-chroman-3-one 
• 853687-49-7 N-[2-[3,4-bis-(tert-butyl-dimethyl-silanyloxy)-phenyl]-5,7-bis-(tert-butyl-dimethyl-silanyloxy)-chroman-3-yl]-3,4,5-tris-(tert-butyl-dimethyl-silanyloxy)-benzamide 
• 853687-50-0 N-[2-[3,4-bis-(tert-butyl-dimethyl-silanyloxy)-phenyl]-5,7-bis-(tert-butyl-dimethyl-silanyloxy)-chroman-3-yl]-3,4,5-tris-(tert-butyl-dimethyl-silanyloxy)-benzamide 
• 853687-46-4 [2-[3,4-bis-(tert-butyl-dimethyl-silanyloxy)-phenyl]-5,7-bis-(tert-butyl-dimethyl-silanyloxy)-chroman-3-yl]-[3,4,5-tris-(tert-butyl-dimethyl-silanyloxy)-benzyl]-amine 
• 853687-44-2 benzyl-[2-[3,4-bis-(tert-butyl-dimethyl-silanyloxy)-phenyl]-5,7-bis-(tert-butyl-dimethyl-silanyloxy)-chroman-3-yl]-amine 
• 853687-45-3 benzyl-[2-[3,4-bis-(tert-butyl-dimethyl-silanyloxy)-phenyl]-5,7-bis-(tert-butyl-dimethyl-silanyloxy)-chroman-3-yl]-amine 
• 853687-47-5 2-[3,4-bis-(tert-butyl-dimethyl-silanyloxy)-phenyl]-5,7-bis-(tert-butyl-dimethyl-silanyloxy)-chroman-3-ylamine 
• 853687-48-6 2-[3,4-bis-(tert-butyl-dimethyl-silanyloxy)-phenyl]-5,7-bis-(tert-butyl-dimethyl-silanyloxy)-chroman-3-ylamine 
• 853687-41-9 N-[(2R,3R)-2-(3,4-Dihydroxy-phenyl)-5,7-dihydroxy-chroman-3-yl]-3,4,5-trihydroxy-benzamide 

Relevant articles and documents

Novel 3C-like protease inhibitor as well as preparation method and application thereof

The invention provides a novel 3C-like protease inhibitor which is 3 ", 4" - O - diacetyl -epicatechin trans-caffeic acid ester with a specific structure. The invention further provides a preparation method and application of the 3C-like protease inhibitor. The invention has the advantages that the compound 3 ", 4" - O - diacetyl - epicatechin trans-caffeic acid ester is designed and synthesized based on the structure of epicatechin; even when the concentration is low, the activity of 3C-like protease in the novel coronavirus can be obviously inhibited. The compounds can be used as 3C-like protease inhibitors and are used for preparing anti-novel coronavirus SARS-CoV - 2 infection drugs.

PYRANS FOR USE IN THE TREATMENT OF INFECTION

There is provided a novel compound of the general formula (I), in which each R is hydrogen, aryl, C1-6 alkyl, trialkylsilyl, or acyl, each R1 is selected from hydroxy, C1-6 alkoxy and acyloxy; each R2 is H, Csu