853929-20-1

Basic information

• Product Name: (2S)-1-(benzyloxy)-8-((tetrahydro-2H-pyran-2-yl)oxy)oct-4-yn-2-ol
• Synonyms: (2S)-1-(benzyloxy)-8-((tetrahydro-2H-pyran-2-yl)oxy)oct-4-yn-2-ol
• CAS NO: 853929-20-1
• Molecular Weight: 332.44
• Mol File: 853929-20-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (2S)-1-(benzyloxy)-8-((tetrahydro-2H-pyran-2-yl)oxy)oct-4-yn-2-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (2S)-1-(benzyloxy)-8-((tetrahydro-2H-pyran-2-yl)oxy)oct-4-yn-2-ol(853929-20-1)
• EPA Substance Registry System: (2S)-1-(benzyloxy)-8-((tetrahydro-2H-pyran-2-yl)oxy)oct-4-yn-2-ol(853929-20-1)

Safety Data

• Hazardous Substances Data: 853929-20-1(Hazardous Substances Data)

Upstream product

• 2930-05-4 Benzyloxymethyl-oxiran 
• 62992-46-5 1-(tetrahydropyranyloxy)-4-pentyn 
• 2930-05-4 (S)-benzyl glycidyl ether 

Downstream Products

• 853929-62-1 C₃₇H₃₈O₆ 
• 853929-65-4 C₃₇H₄₂O₆ 
• 578008-43-2 7(S),17(S)-resolvin D5 
• 853929-33-6 Benzoic acid (S)-1-benzyloxymethyl-6-methoxycarbonyl-hex-3-ynyl ester 
• 853929-30-3 Benzoic acid (S)-1-benzyloxymethyl-7-hydroxy-hept-3-ynyl ester 
• 853929-35-8 Benzoic acid (Z)-(S)-1-benzyloxymethyl-6-methoxycarbonyl-hex-3-enyl ester 
• 853929-44-9 Benzoic acid (Z)-(S)-1-((E)-2-iodo-vinyl)-6-methoxycarbonyl-hex-3-enyl ester 
• 853929-38-1 Benzoic acid (Z)-(S)-1-hydroxymethyl-6-methoxycarbonyl-hex-3-enyl ester 
• 853929-41-6 Benzoic acid (Z)-(S)-1-formyl-6-methoxycarbonyl-hex-3-enyl ester 
• 853929-27-8 Benzoic acid (S)-1-benzyloxymethyl-7-(tetrahydro-pyran-2-yloxy)-hept-3-ynyl ester 

Relevant articles and documents

Formal Synthesis of (+)-Laurencin by Gold(I)-Catalyzed Intramolecular Dehydrative Alkoxylation

8-Membered cyclic ethers are found in a wide range of natural products; however, they are challenging synthetic targets due to enthalpic and entropic barriers. The gold(I)-catalyzed intramolecular dehydrative alkoxylation of ω-hydroxy allylic alcohols was explored to stereoselectively construct α,α′-cis-oxocenes and further applied in a formal synthesis of (+)-laurencin. The gold(I)-catalyzed intramolecular dehydrative alkoxylation may constitute an alternative method for the synthesis of molecular building blocks and natural products that contain highly functionalized 8-membered cyclic ethers.