853998-14-8

Basic information

• Product Name: 4,4,5,5-tetramethyl-2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)-1,3,2-dioxaborolane
• Synonyms: 4,4,5,5-tetramethyl-2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)-1,3,2-dioxaborolane
• CAS NO: 853998-14-8
• Molecular Weight: 314.276
• Mol File: 853998-14-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 4,4,5,5-tetramethyl-2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)-1,3,2-dioxaborolane(CAS DataBase Reference)
• NIST Chemistry Reference: 4,4,5,5-tetramethyl-2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)-1,3,2-dioxaborolane(853998-14-8)
• EPA Substance Registry System: 4,4,5,5-tetramethyl-2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)-1,3,2-dioxaborolane(853998-14-8)

Safety Data

• Hazardous Substances Data: 853998-14-8(Hazardous Substances Data)

Upstream product

• 6683-46-1 1,1,4,4-Tetramethyl-1,2,3,4-tetrahydro-naphthalene 
• 73183-34-3 bis(pinacol)diborane 
• 6223-78-5 2,5-dichloro-2,5-dimethyl hexane 
• 108-86-1 bromobenzene 
• 27452-17-1 6-bromo-1,2,3,4-tetrahydro-1,1,4,4-tetramethylnaphthalene 

Downstream Products

• 1427319-38-7 4-[5-methyl-4-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)thiazol-2-yl]benzoic acid ethyl ester 
• 1378366-94-9 tert-butyl 1-(4-(6-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)pyridin-2-yl)phenyl)cyclobutylcarbamate 
• 1378368-28-5 (rac)-tert-butyl (2-hydroxy-1-(4-(4-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)pyrimidin-2-yl)phenyl)ethyl)carbamate 
• 1312459-92-9 4-[3-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)phenyl]piperazine-1-carboxylic acid tert-butyl ester 
• 288259-76-7 6-(3-bromophenyl)-1,2,3,4-tetrahydro-1,1,4,4-tetramethylnaphthalene 
• 119999-30-3 (Z)-4-<1-(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-2-propenyl>benzenecarbonitrile 

Relevant articles and documents

Nickel(0)-Catalyzed Hydroarylation of Styrenes and 1,3-Dienes with Organoboron Compounds

A Ni-catalyzed hydroarylation of styrenes and 1,3-dienes with organoboron compounds has been developed. The reaction offers a highly selective approach to diarylalkanes and allylarenes under redox-neutral conditions. In this hydroarylation reaction, a new strategy that uses the proton of methanol to generate the active catalyst species Ni?H was developed. The Ni-catalyzed hydroarylation, combined with a Ir-catalyzed C?H borylation, affords a very efficient and straightforward access to a retinoic acid receptor agonist.

Stereoselective synthesis of tetrazole CB92834, a potent retinoid compound

An improved, convergent synthesis of CB92834 is relying on a Suzuki cross-coupling reaction and easily allows multigram-scale preparation of the compound. The approach features three highly stereoselective steps.