854139-75-6

Basic information

• Product Name: 2-[[1,3]dioxolan-2-yl(phenylselenyl)methyl]-3,3-dimethyl-4,4-dioxo-4-thia-1-azabicyclo[3.2.0]heptan-7-one
• Synonyms: 2-[[1,3]dioxolan-2-yl(phenylselenyl)methyl]-3,3-dimethyl-4,4-dioxo-4-thia-1-azabicyclo[3.2.0]heptan-7-one
• CAS NO: 854139-75-6
• Molecular Weight: 430.383
• Mol File: 854139-75-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-[[1,3]dioxolan-2-yl(phenylselenyl)methyl]-3,3-dimethyl-4,4-dioxo-4-thia-1-azabicyclo[3.2.0]heptan-7-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[[1,3]dioxolan-2-yl(phenylselenyl)methyl]-3,3-dimethyl-4,4-dioxo-4-thia-1-azabicyclo[3.2.0]heptan-7-one(854139-75-6)
• EPA Substance Registry System: 2-[[1,3]dioxolan-2-yl(phenylselenyl)methyl]-3,3-dimethyl-4,4-dioxo-4-thia-1-azabicyclo[3.2.0]heptan-7-one(854139-75-6)

Safety Data

• Hazardous Substances Data: 854139-75-6(Hazardous Substances Data)

Upstream product

• 24158-88-1 6,6-dibromopenicillanic acid 
• 854139-82-5 C₁₁H₁₅NO₇S 
• 854139-73-4 3,3-dimethyl-4,4-dioxo-2-[2-(triisopropylsilanyloxy)vinyl]-4-thia-1-azabicyclo[3.2.0]heptan-7-one 
• 854139-70-1 ((2S,5R)-3,3-Dimethyl-4,4,7-trioxo-4λ⁶-thia-1-aza-bicyclo[3.2.0]hept-2-yl)-acetic acid 
• 854139-71-2 2-(2'-hydroxyethyl)-3,3-dimethyl-4,4-dioxo-4-thia-1-azabicyclo[3.2.0]heptan-7-one 
• 854139-72-3 (3,3-dimethyl-4,4,7-trioxo-4-thia-1-azabicyclo[3.2.0]hept-2-yl)acetaldehyde 
• 854139-74-5 (3,3-dimethyl-4,4,7-trioxo-4-thia-1-azabicyclo[3.2.0]hept-2-yl)phenylselenylacetaldehyde 
• 107-21-1 ethylene glycol 
• 118733-55-4 2-diazoacetyl-3,3-dimethyl-4,4-dioxo-4-thia-1-azabicyclo[3.2.0]heptan-7-one 
• 68373-14-8 sulbactum 
• 76646-91-8 6,6-dibromopenicillanic acid-1,1-dioxide 

Relevant articles and documents

Synthesis and evaluation of 3-(carboxymethylidene)- and 3-(carboxymethyl)penicillinates as inhibitors of β-lactamase

Penicillin-resistant bacteria can often be treated through the co-administration of an antibiotic and a β-lactamase inhibitor. Current inhibitors target only class Aβ-lactamases. We report two new series of C3-modified penicillin sulfones, having either a simple methylene group (i.e., a homologue) or exocyclic unsaturation between the thiazolidine ring and the C3 carboxylate. The homologue has 10-fold better activity against a class C β-lactamase than does sulbactam itself. By contrast, the exocyclic C3 unsaturated compounds are less active.