854159-15-2

Basic information

• Product Name: 1-(2-methylsulfanyl-3-pyridyl)-4-tritylpiperazine
• Synonyms: 1-(2-methylsulfanyl-3-pyridyl)-4-tritylpiperazine
• CAS NO: 854159-15-2
• Molecular Weight: 451.635
• Mol File: 854159-15-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-(2-methylsulfanyl-3-pyridyl)-4-tritylpiperazine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-methylsulfanyl-3-pyridyl)-4-tritylpiperazine(854159-15-2)
• EPA Substance Registry System: 1-(2-methylsulfanyl-3-pyridyl)-4-tritylpiperazine(854159-15-2)

Safety Data

• Hazardous Substances Data: 854159-15-2(Hazardous Substances Data)

Upstream product

• 854159-12-9 1-(3-pyridyl)-4-tritylpiperazine 
• 624-92-0 Dimethyldisulphide 
• 67980-77-2 1-(pyridin-3-yl)piperazine 
• 76-83-5 trityl chloride 
• 109-72-8 n-butyllithium 

Downstream Products

• 854159-37-8 1-(2-methylsulfanyl-6-benzoyl-3-pyridyl)-4-tritylpiperazine 
• 854159-36-7 1-(2-iodo-6-methylsulfanyl-3-pyridyl)-4-tritylpiperazine 
• 854159-35-6 1-(2-bromo-6-methylsulfanyl-3-pyridyl)-4-tritylpiperazine 

Relevant articles and documents

First selective lithiation of pyridylpiperazines: Straightforward access to potent pharmacophores

The three isomers of pyridylpiperazines have been lithiated for the first time. The use of a superbase, an aminoalkoxide containing lithiating agent overcomes the chelating influence of the basic piperazine nitrogens, so that selective mono lithiation occurred alpha to pyridine nitrogen. This methodology offers a new access to diverse potent pharmacophores not easily prepared by other routes.