854634-75-6

Basic information

• Product Name: N-([1,1'-biphenyl]-3-yl)-4-methylbenzenesulfonamide
• CAS NO: 854634-75-6
• Molecular Weight: 323.415
• Mol File: 854634-75-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-([1,1'-biphenyl]-3-yl)-4-methylbenzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-([1,1'-biphenyl]-3-yl)-4-methylbenzenesulfonamide(854634-75-6)
• EPA Substance Registry System: N-([1,1'-biphenyl]-3-yl)-4-methylbenzenesulfonamide(854634-75-6)

Safety Data

• Hazardous Substances Data: 854634-75-6(Hazardous Substances Data)

Upstream product

• 98-59-9 p-toluenesulfonyl chloride 
• 941-55-9 4-toluenesulfonyl azide 
• 2243-47-2 3-biphenyl amine 

Downstream Products

• 76129-28-7 4-nitrobiphenyl-3-ylamine 

Relevant articles and documents

Direct C-H amidation of benzoic acids to introduce meta- and para-amino groups by tandem decarboxylation

The Ir-catalyzed mild C-H amidation of benzoic acids with sulfonyl azides was developed to give reactions with high efficiency and functional-group compatibility. Subsequent protodecarboxylation of ortho-amidated benzoic acid products afforded meta- or para-substituted (N-sulfonyl)aniline derivatives, the latter being inaccessible by other C-H functionalization approaches. The decarboxylation step was compatible with the amidation conditions, enabling a convenient one-pot, two-step process. Without a trace: Carboxylic acids are used as traceless directing groups in the Ir-catalyzed direct C-H amidation of arenes with sulfonyl azides under mild conditions. The tandem protodecarboxylation of the ortho-amidated benzoic acid products afforded meta- or para-substituted (N-sulfonyl)anilines, which are difficult to obtain by other C-H functionalization approaches.