85476-35-3Relevant articles and documents
Fucose derivatives, drugs containing the same as active ingredient, and intermediates for producing the same
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, (2008/06/13)
A compound of the formula (I): STR1 wherein X1 is a group of one of the following formulae (1), (2) and (3): STR2 R1 is a branched long chain alkyl group, R2 is --CONHR3, a carboxyl group or a hydrogen atom, n is an integer of 0, 1 or 2, and R3 is a lower alkyl group or a phenyl group, or a pharmaceutically acceptable salt thereof, which is useful as a selectin inhibitor, and can be used in the prophylaxis or treatment of various inflammatory diseases such as inflammatory dermatitis (e.g., atopic dermatitis, contact hypersensitivity, photodermatosis, etc.), autoimmune chronic diseases (e.g. rheumatoid arthritis, chronic thyroiditis, etc.), and ischemia-reperfusion injury.