85484-42-0

Basic information

• Product Name: 6,6’-dimethyl-3,3’-bipyridine
• Synonyms: 6,6’-dimethyl-3,3’-bipyridine
• CAS NO: 85484-42-0
• Molecular Weight: 184.241
• Mol File: 85484-42-0.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 6,6’-dimethyl-3,3’-bipyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 6,6’-dimethyl-3,3’-bipyridine(85484-42-0)
• EPA Substance Registry System: 6,6’-dimethyl-3,3’-bipyridine(85484-42-0)

Safety Data

• Hazardous Substances Data: 85484-42-0(Hazardous Substances Data)

Upstream product

• 626-60-8 3-Chloropyridine 
• 111770-91-3 (6-methylpyridin-3-yl)trifluoromethanesulfonate 
• 626-55-1 3-Bromopyridine 
• 67284-17-7 3-(tosyloxy)pyridine 
• 3430-13-5 5-bromo-2-methylpyridine 
• 21298-53-3 3-thiophen-2-yl-pyridine 
• 110-86-1 pyridine 
• 917-54-4 methyllithium 

Downstream Products

• 1264748-06-2 6,6′-diformyl-3,3′-bipyridine 

Relevant articles and documents

Achieving cell penetration with distance-matching cysteine cross-linkers: A facile route to cell-permeable peptide dual inhibitors of Mdm2/Mdmx

We report the design of bisarylmethylene bromides as a new class of rigid, distance-matching cysteine cross-linkers. By cross-linking a peptide dual inhibitor of Mdm2/Mdmx containing cysteines at i,i+7 positions, dramatic enhancement in cell permeability was achieved, along with increased helicity and biological activity.

Sequential one pot double C[sbnd]H heteroarylation of thiophene using bromopyridines to synthesize unsymmetrical 2,5-bipyridylthiophenes

We present C[sbnd]H heteroarylation reactions between thiophene and variously substituted bromopyridines. The objective was to synthesize unsymmetrical 2,5-bipyridylthiophenes. We studied the reaction conditions allowing to a sequential one-pot double C[sbnd]H heteroarylation, in a view to introduce two different pyridyl moieties at positions 2 and 5 of the thiophene ring using bromopyridines. 11 original unsymmetrical 2,5-bipyridylthiophenes were synthesized and characterized, including 2,5-di(pyridin-2-yl)thiophenes for which the preparation by classical cross-coupling reactions is challenging. Finally, with the additional synthesis of both an unsymmetrical 2,5-biarylthiophene and an original pyrimidin-thiophene-furan scaffold, we shown that our methodology was also an efficient tool to access to new heterocyclic sequences.

Experimental and computational probes of a self-assembled capsule

This research was undertaken to explore the interior surface of a synthetic receptor 1.1 with arylpyridines as guests. The interior surface differentiates the guests through the recognition of their nitrogen atoms. Experimental and computational analyses revealed that there is a delicate balance of attractions and repulsions between the host and the lone pairs of guests.