85508-99-2

Basic information

• Product Name: 4-BROMO-3-METHYL-ISOTHIAZOL-5-YLAMINE
• Synonyms: 4-BroMo-3-Methylisothiazol-5-aMine;4-bromo-3-methyl-5-Isothiazolamine;4-BROMO-3-METHYL-ISOTHIAZOL-5-YLAMINE;5-AMINO-4-BROMO-3-METHYLISOTHIAZOLE
• CAS NO: 85508-99-2
• Molecular Formula: C₄H₅BrN₂S
• Molecular Weight: 193.0649
• Mol File: 85508-99-2.mol
• Article Data: 6

Chemical Properties

• Melting Point: 102-106°C
• Boiling Point: 154.5 °C at 760 mmHg
• Flash Point: 47.2 °C
• Appearance: /
• Density: 1.806 g/cm³
• Storage Temp.: 2-8°C
• PKA: 6.37±0.50(Predicted)
• CAS DataBase Reference: 4-BROMO-3-METHYL-ISOTHIAZOL-5-YLAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-BROMO-3-METHYL-ISOTHIAZOL-5-YLAMINE(85508-99-2)
• EPA Substance Registry System: 4-BROMO-3-METHYL-ISOTHIAZOL-5-YLAMINE(85508-99-2)

Safety Data

• Hazard Codes: Xn
• Statements: 22-37/38-41
• Safety Statements: 26-39
• WGK Germany: 3
• Hazardous Substances Data: 85508-99-2(Hazardous Substances Data)

Usage

General Description

4-Bromo-3-methyl-isothiazol-5-ylamine is a chemical compound that belongs to the class of isothiazole compounds. It is commonly used as a biocide and preservative in a variety of industrial and consumer products, including personal care products, paints, adhesives, and cooling water systems. Its antimicrobial properties make it effective in inhibiting the growth of bacteria, fungi, and algae, thus extending the shelf life and maintaining the quality of the products it is used in. However, there have been concerns raised about its potential health hazards, particularly its skin and respiratory irritant properties, leading to regulations on its use and maximum allowable concentrations in certain applications. Nevertheless, 4-Bromo-3-methyl-isothiazol-5-ylamine continues to be an important and widely used chemical in various industries.

Upstream product

• 24340-76-9 3-methyl-5-aminothiazole 
• 71134-43-5 3-methyl-5-aminoisothiazole hydrochloride 

Downstream Products

• 1732-55-4 4,5-dibromo-3-methyl-isothiazole 
• 930-42-7 4-bromo-3-methylisothiazole 

Relevant articles and documents

GPR40 AGONISTS FOR THE TREATMENT OF TYPE II DIABETES

Disclosed are compounds, compositions and methods for treating of disorders that are affected by the modulation of the GPR40 receptor. Such compounds are represented by Formula II.

GPR40 AGONISTS FOR THE TREATMENT OF TYPE II DIABETES

Disclosed are compounds, compositions and methods for treating of disorders that are affected by the modulation of the GPR40 receptor. Such compounds are represented by Formula (III); wherein R1c, R2C, R4C, Wc, Yc, Zc and Gc, are defined herein.

Imidazopyrazines as protein kinase inhibitors

In its many embodiments, the present invention provides a novel class of imidazopyrazine compounds as inhibitors of protein and/or checkpoint kinases, methods of preparing such compounds, pharmaceutical compositions including one or more such compounds, methods of preparing pharmaceutical formulations including one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the protein or checkpoint kinases using such compounds or pharmaceutical compositions.