85511-68-8 Usage
General Description
1H-Indole-2,3-dione, 7-chloro-1-[[4-(trifluoromethyl)phenyl]methyl]-, also known as TFMFPI, is a chemical compound with a complex molecular structure. It is a derivative of indole-2,3-dione that contains a chlorine atom and a trifluoromethylphenylmethyl group. TFMFPI is a potential drug candidate with a wide range of biological activities, including antifungal, anticancer, and anti-inflammatory properties. 1H-Indole-2,3-dione, 7-chloro-1-[[4-(trifluoromethyl)phenyl]methyl]- is of interest to researchers in the pharmaceutical and chemical industries for its possible applications in drug development and medical research.
Check Digit Verification of cas no
The CAS Registry Mumber 85511-68-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,5,5,1 and 1 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 85511-68:
(7*8)+(6*5)+(5*5)+(4*1)+(3*1)+(2*6)+(1*8)=138
138 % 10 = 8
So 85511-68-8 is a valid CAS Registry Number.
85511-68-8Relevant articles and documents
Discovery of the first highly M5-preferring muscarinic acetylcholine receptor ligand, an M5 positive allosteric modulator derived from a series of 5-trifluoromethoxy N-benzyl isatins
Bridges, Thomas M.,Marlo, Joy E.,Niswender, Colleen M.,Jones, Carrie K.,Jadhav, Satyawan B.,Gentry, Patrick R.,Plumley, Hyekyung C.,Weaver, C. David,Conn, P. Jeffrey,Lindsley, Craig W.
supporting information; experimental part, p. 3445 - 3448 (2010/04/02)
This report describes the discovery and initial characterization of the first positive allosteric modulator of muscarinic acetylcholine receptor subtype 5 (mAChR5 or M5). Functional HTS, identified VU0119498, which displayed micromolar potencies for poten