855256-87-0Relevant articles and documents
Asymmetric total synthesis of 5′-epi-paecilomycin-F
Jana, Nandan,Nanda, Samik
, p. 802 - 808 (2012/09/07)
The asymmetric total synthesis of one of the stereoisomers of the naturally occurring 14-membered ring macrolide paecilomycin-F (5′-epi) has been reported in this article. The main highlight of the synthetic strategy involves the successful application of
Total syntheses of natural tubelactomicins B, D, and E: Establishment of their stereochemistries
Sawamura, Kiyoto,Yoshida, Keigo,Suzuki, Akari,Motozaki, Toru,Kozawa, Ikuko,Hayamizu, Takashi,Munakata, Ryosuke,Takao, Ken-Ichi,Tadano, Kin-Ichi
, p. 6143 - 6148 (2008/02/10)
(Chemical Equation Presented) Total syntheses of the antimicrobial tricyclic 16-membered macrolides, (+)-tubelactomicin B, (+)-tubelactomicin D, and (+)-tubelactomicin E, have been accomplished for the first time with common synthetic approaches. These total syntheses established the relative and absolute configurations of the three tubelactomicins, for which planar structures had solely been reported. The total synthesis of (+)-tubelactomicin D included a newly developed stereoselective intramolecular Diels-Alder reaction for constructing the highly functionalized octahydronaphthalene substructures.
Stereoselective synthesis of (+)-diplodialides-B, C and a formal synthesis of (+)-diplodialide-A by ring-closing metathesis approach
Sharma,Reddy, K. Laxmi
, p. 3197 - 3202 (2007/10/03)
Stereoselective synthesis of diplodialides-B and C and the formal synthesis of diplodialide-A are reported. A combination of Jacobsen's hydrolytic kinetic resolution and Sharpless epoxidation is used for the creation of two stereogenic centers, while a ring-closing metathesis strategy was used for the construction of the lactone ring.
