85547-56-4 Usage
General Description
4,4'-(1,3-Propanediyldi-4,1-piperazinediyl)bis(7-chloroquinoline) phosphate is a chemical compound with the molecular formula C34H32Cl2N6O4P. It is a phosphate salt derived from 7-chloroquinoline, a compound with anti-malarial properties. This particular derivative is a dimer of 7-chloroquinoline linked by a 1,3-propanediyldi-4,1-piperazinediyl bridge, and it is utilized as a medication for the treatment and prevention of malaria. Additionally, such compounds have also shown potential as antitumor agents due to their ability to intercalate DNA and prevent its replication. However, further research is needed to fully understand the potential therapeutic applications of 4,4'-(1,3-Propanediyldi-4,1-piperazinediyl)bis(7-chloroquinoline) phosphate.
Check Digit Verification of cas no
The CAS Registry Mumber 85547-56-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,5,5,4 and 7 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 85547-56:
(7*8)+(6*5)+(5*5)+(4*4)+(3*7)+(2*5)+(1*6)=164
164 % 10 = 4
So 85547-56-4 is a valid CAS Registry Number.
InChI:InChI=1/C29H32Cl2N6.H3O4P/c30-22-2-4-24-26(20-22)32-8-6-28(24)36-16-12-34(13-17-36)10-1-11-35-14-18-37(19-15-35)29-7-9-33-27-21-23(31)3-5-25(27)29;1-5(2,3)4/h2-9,20-21H,1,10-19H2;(H3,1,2,3,4)
85547-56-4Relevant articles and documents
AN IMPROVED PROCESS FOR THE PREPARATION OF PIPERAQUINE
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Page/Page column 11-12, (2011/09/14)
The present invention relates to an improved process for the preparation of 7-chloro- 4-piperazin-1-yl-quinoline of formula (I), a key intermediate for the synthesis of Piperaquine or its pharmaceutically acceptable salts.
