85583-39-7

Basic information

• Product Name: 4-[2-(4,6-dimethyl-2-pyridyl)ethoxy]aniline
• Synonyms: 4-[2-(4,6-dimethyl-2-pyridyl)ethoxy]aniline
• CAS NO: 85583-39-7
• Molecular Weight: 242.321
• Mol File: 85583-39-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-[2-(4,6-dimethyl-2-pyridyl)ethoxy]aniline(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[2-(4,6-dimethyl-2-pyridyl)ethoxy]aniline(85583-39-7)
• EPA Substance Registry System: 4-[2-(4,6-dimethyl-2-pyridyl)ethoxy]aniline(85583-39-7)

Safety Data

• Hazardous Substances Data: 85583-39-7(Hazardous Substances Data)

Upstream product

• 85583-53-5 2,4-Dimethyl-6-[2-(4-nitro-phenoxy)-ethyl]-pyridine 
• 13287-63-3 2-(4,6-dimethylpyridin-2-yl)ethanol 
• 350-46-9 4-Fluoronitrobenzene 

Downstream Products

• 127676-20-4 Methyl 2-bromo-3-<4-<2-(4,6-dimethyl-2-pyridyl)ethoxy>phenyl>propionate 
• 127676-26-0 5-{4-[2-(4,6-Dimethyl-pyridin-2-yl)-ethoxy]-benzyl}-2-imino-thiazolidin-4-one 
• 127676-13-5 5-[4-[2-(4,6-dimethyl-2-pyridyl)ethoxy]benzyl]-2,4-thiazolidinedione 
• 101946-32-1 methyl 3-{4-[2-acetoxy-2-(4,6-dimethyl-pyridin-2-yl)ethoxy]phenyl}-2-bromopropionate 

Relevant articles and documents

Studies on antidiabetic agents. Synthesis and hypoglycemic activity of 5-[4-(pyridylalkoxy)benzyl]-2,4-thiazolidinediones

The synthesis of a series of 5-[4-(pyridylalkoxy)benzyl]-2,4-thiazolidinediones is described. These compounds were evaluated for hypoglycemic and hypolipidemic activities in genetically obese and diabetic mice, yellow KK. 2-(2-Pyridyl)alkoxy derivatives were found to have much better hypoglycemic and hypolipidemic activities than 2-(3-pyridyl)- and 2-(4-pyridyl)alkoxy derivatives or even the previously reported compound, ciglitazone. The introduction of a hydroxyl group at the 2-position of the ethoxy chain potentiated the activities. Among the potent compounds, pioglitazone (AD-4833) was selected as a candidate compound.