85598-13-6

Basic information

• Product Name: 1-BroMo-4-Methoxy-2-Methyl-3-nitrobenzene
• Synonyms: 1-BroMo-4-Methoxy-2-Methyl-3-nitrobenzene
• CAS NO: 85598-13-6
• Molecular Formula: C₈H₈BrNO₃
• Molecular Weight: 246.05802
• Mol File: 85598-13-6.mol
• Article Data: 10

Chemical Properties

• Melting Point: 97-99 °C(Solv: benzene (71-43-2))
• Boiling Point: 317.0±37.0 °C(Predicted)
• Appearance: /
• Density: 1.559±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 1-BroMo-4-Methoxy-2-Methyl-3-nitrobenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-BroMo-4-Methoxy-2-Methyl-3-nitrobenzene(85598-13-6)
• EPA Substance Registry System: 1-BroMo-4-Methoxy-2-Methyl-3-nitrobenzene(85598-13-6)

Safety Data

• Hazardous Substances Data: 85598-13-6(Hazardous Substances Data)

Usage

Description

1-Bromo-4-methoxy-2-methyl-3-nitrobenzene is a chemical compound with the molecular formula C8H8BrNO3. It is a nitrobenzene derivative that contains a bromine atom, a methoxy group, and a methyl group attached to the benzene ring. This yellow crystalline solid with a slightly sweet odor is used as a building block in organic synthesis for the production of various pharmaceuticals, agrochemicals, and dyes. It also serves as an intermediate in the manufacturing of other chemicals.

Uses

Used in Pharmaceutical Industry:
1-Bromo-4-methoxy-2-methyl-3-nitrobenzene is used as a building block for the synthesis of various pharmaceuticals, contributing to the development of new drugs and therapeutic agents.
Used in Agrochemical Industry:
In the agrochemical industry, 1-Bromo-4-methoxy-2-methyl-3-nitrobenzene is utilized as a precursor in the synthesis of agrochemicals, aiding in the production of pesticides and other agricultural chemicals.
Used in Dye Industry:
1-Bromo-4-methoxy-2-methyl-3-nitrobenzene is employed as a starting material in the synthesis of dyes, playing a role in the creation of colorants for various applications.
Used in Chemical Intermediates:
As an intermediate in chemical manufacturing, 1-Bromo-4-methoxy-2-methyl-3-nitrobenzene is used to produce a range of other chemicals, expanding its utility across different chemical processes.

Upstream product

• 85598-12-5 4-bromo-3-methyl-2-nitro-phenol 
• 74-88-4 methyl iodide 
• 4920-77-8 3-methyl-2-nitrophenol 
• 108-39-4 3-methyl-phenol 
• 5345-42-6 1-methoxy-3-methyl-2-nitro-benzene 
• 27060-75-9 4-bromo-3-methylanisole 

Downstream Products

• 85598-14-7 2-Nitro-3-methyl-4-cyanoanisole 
• 786596-55-2 2-Methyl-3-bromo-6-methoxyaniline 
• 436091-59-7 4-bromo-7-methoxy-1H-indole 
• 436097-25-5 1-bromo-3-[7-methoxy-1-(toluene-4-sulfonyl)-1H-indol-4-yl]-butan-2-one 
• 436093-85-5 1-hydroxy-3-[7-methoxy-1-(toluene-4-sulfonyl)-1H-indol-4-yl]-butan-2-one 
• 436097-24-4 methanesulfonic acid 3-[7-methoxy-1-(toluene-4-sulfonyl)-1H-indol-4-yl]-2-oxo-butyl ester 
• 436092-17-0 (2R,3S)-3-(7-Methoxy-1H-indol-4-yl)-1-trityloxy-butan-2-ol 
• 436091-30-4 N-(5-{1-[7-methoxy-1-(toluene-4-sulfonyl)-1H-indol-4-yl]-ethyl}-1H-imidazol-2-yl)-acetamide 
• 436091-70-2 3-[1-(tert-butyl-dimethyl-silanyl)-7-methoxy-1H-indol-4-yl]-1-trityloxy-butan-2-ol 
• 436093-34-4 (2R,3S)-3-[7-Methoxy-1-(toluene-4-sulfonyl)-1H-indol-4-yl]-1-trityloxy-butan-2-ol 
• 85628-22-4 N,N-Dimethyl-2-(2-nitro-3-methoxy-6-cyanophenyl)ethenamine 
• 85598-19-2 N-(p-Toluenesulfonyl)-4-chloromethyl-7-methoxyindole 
• 85598-18-1 N-(p-Toluenesulfonyl)-4-hydroxymethyl-7-methoxyindole 
• 85598-17-0 N-(p-Toluenesulfonyl)-4-formyl-7-methoxyindole 

Relevant articles and documents

AURORA AND FLT3 KINASES MODULATORS

The invention provides a compound having the formula (1): and salts thereof; wherein: R1 is hydrogen or C1-2 alkyl; and R2, R3 and R4 are the same or different and each is selected from hydrogen, C1-2 alkyl, fluorine, chlorine, C1-2 alkoxy and trifluoromethyl, provided that no more than two of R2, R3 and R4 are other than hydrogen. Also provided are pharmaceutical compositions containing the compounds and their use in medicine, and in particular in the treatment of cancer.

AURORA AND FLT3 KINASES MODULATORS

The invention provides a compound having the formula (1) useful as modulator of the activity of Aurora kinases and FLT3 kinases: and salts thereof; wherein: R1 is hydrogen or C1-2 alkyl; and R2, R3 and R4 are the same or different and each is selected from hydrogen, C1-2 alkyl, fluorine, chlorine, C1-2 alkoxy and trifluoromethyl, provided that no more than two of R2, R3 and R4 are other than hydrogen. Also provided are pharmaceutical compositions containing the compounds and their use in medicine, and in particular in the treatment of cancer

TETRACYCLIC XANTHENE DERIVATIVES AND METHODS OF USE THEREOF FOR TREATMENT OF VIRAL DISEASES

The present invention discloses tetracyclic xanthene derivatives of Formula (I) and pharmaceutically acceptable salts thereof, wherein A, Y1, Y2, Z, Ra, Rb, R1a, R1b, and R2 are as defined herein. The present invention also discloses compositions comprising at least one tetracyclic xanthene derivative, and methods of using the tetracyclic xanthene derivatives for treating or preventing HCV infection in a patient.