85612-29-9Relevant articles and documents
Synthesis of (-)-lapatin B
Walker, Steven J.,Hart, David J.
, p. 6214 - 6216 (2007)
The synthesis of (-)-lapatin B (1) has been achieved from l-tryptophan. The key reactions involve oxidative cyclization of N,N-diacetylglyantrypine (8) using PhI(OH)(OTs), and an indole-to-oxindole transformation in the penultimate step.
Synthesis of new proteomimetic quinazolinone alkaloids and evaluation of their neuroprotective and antitumor effects
Long, Solida,Resende, Diana I.S.P.,Kijjoa, Anake,Silva, Artur M.S.,Fernandes, Ricardo,Xavier, Cristina P.R.,Vasconcelos, M. Helena,Sousa, Emília,Pinto, Madalena M.M.
, (2019/02/28)
New quinazolinone derivatives of the marine-derived alkaloids fiscalin B (3) and fumiquinazoline G (1), with neuroprotective and antitumor effects, were synthesized. Eleven quinazolinone-containing indole alkaloids were synthesized, proceeding the anti an
Synthesis of ent-alantrypinone
Hart,Magomedov
, p. 5892 - 5899 (2007/10/03)
This paper presents a synthesis of ent-alantrypinone (ent-6), the enantiomer of a natural product produced by the fungus Penicillium thymicola. The synthesis revolves around the Li[Me3AlSPh]-promoted isomerization of iminobenzoxazine 33 to quin