85658-60-2

Basic information

• Product Name: 2-amino-6-methyl-4-phenylpyrimidine 1-oxide
• Synonyms: 2-amino-6-methyl-4-phenylpyrimidine 1-oxide
• CAS NO: 85658-60-2
• Molecular Weight: 201.228
• Mol File: 85658-60-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-amino-6-methyl-4-phenylpyrimidine 1-oxide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-amino-6-methyl-4-phenylpyrimidine 1-oxide(85658-60-2)
• EPA Substance Registry System: 2-amino-6-methyl-4-phenylpyrimidine 1-oxide(85658-60-2)

Safety Data

• Hazardous Substances Data: 85658-60-2(Hazardous Substances Data)

Upstream product

• 15755-15-4 2-amino-6-methyl-4-phenylpyrimidine 
• 7788-14-9 5-phenyl-1,2,4-oxadiazol-3-amine 
• 106124-27-0 3-(5-methyl-[1,2,4]oxadiazol-3-ylamino)-1-phenyl-but-2-en-1-one 
• 106124-30-5 4-Methyl-1-oxy-6-phenyl-pyrimidin-2-ylamine 
• 108656-08-2 N-(6-Methyl-1-oxy-4-phenyl-pyrimidin-2-yl)-benzamide 
• 40483-47-4 5-methyl-[1,2,4]oxadiazol-3-ylamine 
• 93-91-4 1-phenylbutan-1,3-dione 

Downstream Products

• 108656-09-3 N-(6-Methyl-1-oxy-4-phenyl-pyrimidin-2-yl)-acetamide 
• 78664-23-0 2-chloro-6-methyl-4-phenylpyrimidine 1-oxide 

Relevant articles and documents

Heterocyclic Rearrangements. Synthesis of 1,2,4-Oxadiazolopyrimidinium Systems and Their Ring Opening into Pyrimidine N-Oxides

The reaction of 3-amino-5-phenyl-(methyl)-1,2,4-oxadiazole with acetylacetone or benzoylacetone in the presence of perchloric acid has been studied.Synthesis of 1,2,4-oxadiazolopyrimidinium perchlorates and their ring opening reaction into aminopyrimidine N-oxides is reported.

Transformations of 2-Aminopyrimidines and Their N-Oxides under Diazotation Conditions

The diazotation of 2-aminopyrimidines and their N-oxides in solutions with various acidities was studied.It is shown that the amino group in pyrimidine N-oxides is not diazotized in strongly acidic media and that bromination in the 5 position of the pyrimidine ring is observed in concentrated hydrobromic acid.When the reaction was carried out in moderately acidic media, it was possible to synthesize the difficult-to-obtain 2-halopyrimidine N-oxides.