85676-74-0

Basic information

• Product Name: Benzene, 1-chloro-2-[2-(4-methoxyphenyl)ethenyl]-, (E)-
• CAS NO: 85676-74-0
• Molecular Formula: C15H13ClO
• Molecular Weight: 244.721
• Mol File: 85676-74-0.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: Benzene, 1-chloro-2-[2-(4-methoxyphenyl)ethenyl]-, (E)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-chloro-2-[2-(4-methoxyphenyl)ethenyl]-, (E)-(85676-74-0)
• EPA Substance Registry System: Benzene, 1-chloro-2-[2-(4-methoxyphenyl)ethenyl]-, (E)-(85676-74-0)

Safety Data

• Hazardous Substances Data: 85676-74-0(Hazardous Substances Data)

Upstream product

• 2039-87-4 2-chlorostyrene 
• 93296-09-4 4-methoxyphenylzinc chloride 
• 696-62-8 para-iodoanisole 
• 18583-55-6 2-chlorobenzyl-triphenylphosphonium chloride 
• 123-11-5 4-methoxy-benzaldehyde 
• 2746-25-0 p-Methoxybenzyl bromide 
• 1145-93-3 diethyl 4-methoxybenzylphosphonate 
• 89-98-5 2-chloro-benzaldehyde 
• 3462-97-3 (4-methoxybenzyl)triphenylphosphonium bromide 
• 943-89-5 (E)-3-(4-methoxyphenyl)acrylic acid 
• 95-51-2 o-chloroaniline 

Downstream Products

• 1449779-41-2 2-bromo-1-(2-chlorophenyl)-2-(4-methoxyphenyl)ethanone 

Relevant articles and documents

An Interrupted Pummerer/Nickel-Catalysed Cross-Coupling Sequence

An interrupted Pummerer/nickel-catalysed cross-coupling strategy has been developed and used in the elaboration of styrenes. The operationally simple method can be carried out as a one-pot process, involves the direct formation of stable alkenyl sulfonium salt intermediates, utilises a commercially available sulfoxide, catalyst, and ligand, operates at ambient temperature, accommodates sp-, sp2-, and sp3-hybridised organozinc coupling partners, and delivers functionalised styrene products in high yields over two steps. An interrupted Pummerer/cyclisation approach has also been used to access carbo- and heterocyclic alkenyl sulfonium salts for cross-coupling.

THERAPEUTIC AGENTS FOR SKIN DISEASES AND CONDITIONS

The present invention relates to method(s) of treating a subject afflicted with a skin disease or condition, the method comprising administering to the subject or patient in need a composition comprising a therapeutically effective amount of a substituted cis or trans- stilbene or a stilbene hybrid. A method of treating or reducing the likelihood of a skin disease or condition in a patient is an additional embodiment of the present invention. Preferred pharmaceutical compositions of the invention include nanoemulsions comprising a therapeutically effective amount of a substituted cis or trans-stilbene or stilbene hybrid and at least one antibiotic.

Visible light-mediated oxidative quenching reaction to electron-rich epoxides: Highly regioselective synthesis of α-bromo (di)ketones and mechanism study

A novel and simple procedure was developed for the regioselective synthesis of α-bromo (di)ketones from electron-rich epoxides via visible light photoredox catalysis. Through optimization of solvent and light source, the reaction can be rapidly achieved under mild conditions. Moreover, the possible reaction mechanism was proposed and further supported by control experiments.