856765-68-9 Usage
Description
Ethyl trans-Cinnamate-d5 is an isotope-labeled organic compound that serves as a key intermediate in the synthesis of various pharmaceuticals and chemical reactions. Its unique deuterium-labeled structure allows for enhanced analytical capabilities and improved understanding of reaction mechanisms.
Uses
Used in Pharmaceutical Industry:
Ethyl trans-Cinnamate-d5 is used as a key intermediate for the preparation of polymer-encapsulated osmonium, which acts as a catalyst for the dihydroxylation of alkenes. This process is crucial in the synthesis of camptothecin, an anticancer drug that has significant applications in cancer treatment.
Used in Cancer Research:
Ethyl trans-Cinnamate-d5 is utilized in the synthesis of substrate-specific ERK1/2 inhibitors, which play a vital role in inducing apoptosis and inhibiting cell proliferation. These inhibitors are essential tools in understanding the molecular mechanisms of cancer and developing targeted therapies for various types of cancer.
Used in Chemical Reactions:
Ethyl trans-Cinnamate-d5 is used as a deuterated analog in various chemical reactions, providing valuable insights into reaction kinetics and mechanisms. Its deuterium-labeled structure allows researchers to differentiate between similar compounds and monitor reaction progress more effectively.
Check Digit Verification of cas no
The CAS Registry Mumber 856765-68-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,5,6,7,6 and 5 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 856765-68:
(8*8)+(7*5)+(6*6)+(5*7)+(4*6)+(3*5)+(2*6)+(1*8)=229
229 % 10 = 9
So 856765-68-9 is a valid CAS Registry Number.
856765-68-9Relevant articles and documents
Isotope labeled 'HEA Moiety' in the synthesis of labeled HIV-protease inhibitors - Part 1
Ekhato, I. Victor,Liao, Yuan,Plesescu, Mihaela
, p. 821 - 835 (2007/10/03)
[(S)-1′-((N-tert-Butyloxycarbonyl)amino)-2S-[2H 5]phenyl-ethyl]oxirane 11, made from [2H 5]-bromobenzene, was transformed into the HIV-protease inhibitors [2H5J-DPH 153893 and [2H5]-DPH 140
