856908-41-3

Basic information

• Product Name: methyl (Z)-3-hydroxy-2-methoxyimino-3-phenylpropionate
• Synonyms: methyl (Z)-3-hydroxy-2-methoxyimino-3-phenylpropionate
• CAS NO: 856908-41-3
• Molecular Weight: 223.229
• Mol File: 856908-41-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: methyl (Z)-3-hydroxy-2-methoxyimino-3-phenylpropionate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl (Z)-3-hydroxy-2-methoxyimino-3-phenylpropionate(856908-41-3)
• EPA Substance Registry System: methyl (Z)-3-hydroxy-2-methoxyimino-3-phenylpropionate(856908-41-3)

Safety Data

• Hazardous Substances Data: 856908-41-3(Hazardous Substances Data)

Upstream product

• 856908-46-8 phenylmethyl (Z)-4,5-dihydro-N-methoxy-4,4-dimethyl-2-oxazolecarboximidate 

Downstream Products

• 38114-29-3 erythro-methyl 2-amino-3-hydroxy-3-phenylpropanoate 

Relevant articles and documents

Stereoselective synthesis of β-hydroxyphenylalanines using imino 1,2-Wittig rearrangement of hydroximates

The imino 1,2-Wittig rearrangement of hydroximates containing a furan ring provides a novel method for the synthesis of β-hydroxy-α-amino acids. Upon treatment with LDA, hydroximates smoothly underwent the rearrangement to give Z-2-hydroxyoxime ethers in good yield, which were converted into both cis- and trans-oxazolidinones with high stereoselectivity. The cis- and trans-oxazolidinones were stereoselectively converted into erythro- and thereo-β-hydroxypheny lalanines, respectively, via the oxidative cleavage of a furan ring, ring-opening of oxazolidinone, and deprotection.