857-30-7

Basic information

• Product Name: 1H-Pyrrole, 1-(4-nitrophenyl)-2,5-diphenyl-
• Synonyms: 1-(4-Nitro-phenyl)-2,5-diphenyl-1H-pyrrole;1-(4-nitrophenyl)-2,5-diphenyl-1H-pyrrole;1-(4-nitro-phenyl)-2,5-diphenyl-pyrrole;1-(4-nitrophenyl)-2,5-diphenylpyrrole
• CAS NO: 857-30-7
• Molecular Formula: C22H16N2O2
• Molecular Weight: 340.381
• Mol File: 857-30-7.mol
• Article Data: 3

Chemical Properties

• Melting Point: 253 °C
• Boiling Point: 542.3±38.0 °C(Predicted)
• Density: 1.17±0.1 g/cm3(Predicted)
• CAS DataBase Reference: 1H-Pyrrole, 1-(4-nitrophenyl)-2,5-diphenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrrole, 1-(4-nitrophenyl)-2,5-diphenyl-(857-30-7)
• EPA Substance Registry System: 1H-Pyrrole, 1-(4-nitrophenyl)-2,5-diphenyl-(857-30-7)

Safety Data

• Hazardous Substances Data: 857-30-7(Hazardous Substances Data)

Usage

Molecular Structure

1H-Pyrrole, 1-(4-nitrophenyl)-2,5-diphenylis a chemical compound that contains a pyrrole ring with a 4-nitrophenyl group and two phenyl groups attached.

Usage

It is commonly used in the field of organic chemistry as a building block for the synthesis of various organic compounds.

Potential Applications

This chemical has potential applications in the pharmaceutical industry for the development of new drugs, as well as in the field of materials science for the production of new materials with specific properties.

Handling Precautions

It is important to handle this chemical with care, as it may pose health and environmental hazards if not used properly.

Upstream product

• 886-66-8 1,4-diphenyl-1,3-butadiyne 
• 100-01-6 4-nitro-aniline 
• 495-71-6 phenacylacetophenone 

Downstream Products

• 359623-74-8 1-(4-nitrophenyl)-2,5-diphenyl-1H-pyrrole-3-carbaldehyde 
• 188483-20-7 5-benzoyl-3-phenylisothiazole 

Relevant articles and documents

TTF derivative of 2,5-aromatic disubstituted pyrrole, synthesis and electronic study

TTF derivative of substituted pyrrole was obtained by means electrochemical synthesis, the resultant colored mix was characterized by Mass spectrometry, NMR and EPR studies, its intrinsic electronic behavior was measured by a four point probe method, besides theoretical calculations were carried out on the possible structures of the resultant molecular adduct. All the results show that there is a net transfer of an electron between both organic moieties in solution giving place to a semiconductor species.

Conversion of pyrroles into bi-1,2,5-thiadiazoles: A new route to biheterocycles

Trithiazyl trichloride 1 converts 1,2,5-triphenylpyrrole 5 into its 3,4-dichloro derivative together with the isothiazole imine 6 and the imine hydrolysis product, the ketone 3. The best yield of the isothiazole 6 is obtained in the presence of 4 A molecular sieves (Table 1). Conversion of the pyrrole 5 into the isothiazole 6 is exactly analogous to the reaction of 1 with 2,5-diphenyl-furan and -thiophene. Other N-aryl and the related 2,5-diphenylpyrroles 8 give similar results (Table 2). However, 1-methyl-2,5-diphenylpyrrole 11 reacts with 1 in an entirely different way to give 4,4′-diphenyl-3,3′-bi-1,2,5-thiadiazole 12, in which two thiadiazole rings have been fused onto the pyrrole and the CH3N unit has been excised as HCN. The same product 12 is formed, in similar yields, by reaction of 1 with 1,4-diphenylbuta-1, 3-diyne and 1,4-diphenylbut-1-en-3-yne. Other N-alkyl 2,5-diphenylpyrroles 16 react similarly (Table 3), giving the best yield (70%) of bi-thiadiazole 12 in the presence of 4 A molecular sieves (Table 4). 1-Methyl- and 1-ethyl-3,4-dibromo-2,5-diphenylpyrrole also give 12, together with 3-(benzoyldichloromethyl)-4-phenyl-1,2,5-thiadiazole 21 in high combined yield. The formation of bi-1,2,5-thiadiazole 12 from N-alkylpyrroles represents a new dissection of the pyrrole ring and a new and very short route to an aromatic biheterocyclic system. Mechanisms which rationalise the different pathways observed are proposed for all of these reactions.