857680-51-4

Basic information

• Product Name: C₃₅H₂₂N₄O₁₃
• Synonyms: C₃₅H₂₂N₄O₁₃
• CAS NO: 857680-51-4
• Molecular Weight: 706.579
• Mol File: 857680-51-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₃₅H₂₂N₄O₁₃(CAS DataBase Reference)
• NIST Chemistry Reference: C₃₅H₂₂N₄O₁₃(857680-51-4)
• EPA Substance Registry System: C₃₅H₂₂N₄O₁₃(857680-51-4)

Safety Data

• Hazardous Substances Data: 857680-51-4(Hazardous Substances Data)

Upstream product

• 150-13-0 4-amino-benzoic acid 
• 17057-04-4 N-(4-carboxyphenyl)maleimide 
• 29305-46-2 4-(2,5-dioxo-2,5-dihydro-1-pyrrol-1-yl)benzoyl chloride 
• 857680-49-0 5-(4-(2,5-dioxo-2H-pyrrol-1⁽⁵⁾-yl)benzamido)isophthalic acid 
• 857680-50-3 5-[4-(2,5-dioxo-2,5-dihydro-pyrrol-1-yl)-benzoylamino]-isophthaloyl dichloride 
• 99-31-0 5-aminoisophthalic acid 

Downstream Products

• 857680-52-5 C₃₅H₁₈Cl₄N₄O₉ 

Relevant articles and documents

Hemoglobin-superoxide dismutase-chemical linkages that create a dual-function protein

Chemical reagents were designed to cross-link and connect hemoglobin and superoxide dismutase, combining the oxygen transport and superoxide-removal capabilities of the red cell in a dual-function protein. Reaction of 1 with thiol-protected hemoglobin followed by reduction produces cross-linked hemoglobin with a free thiol on the cross-link. Reaction of SOD with 5 produces a cross-linked protein with a maleimide on the cross-link. Addition of the hemoglobin-thiol to the SOD-maleimide produces a protein with the desired dual properties. Hemoglobin's oxygenation cooperativity is lowered as a result of being in the conjugate, while SOD's activity is equal to that of the native protein.