857801-97-9

Basic information

• Product Name: 6-Nitro-3-indazolecarboxylic acid
• Synonyms: 6-NITRO-3-INDAZOLECARBOXYLIC ACID;6-NITRO INDAZOLE-3-CARBOXYLIC ACID;6-NITRO-(1H)INDAZOLE-3-CARBOXYLIC ACID;1H-Indazole-3-carboxylic acid, 6-nitro-
• CAS NO: 857801-97-9
• Molecular Formula: C8H5N3O4
• Molecular Weight: 207.14
• Mol File: 857801-97-9.mol
• Article Data: 4

Chemical Properties

• Melting Point: 268 °C (decomp)
• Boiling Point: 547.1 °C at 760 mmHg
• Flash Point: 284.7 °C
• Appearance: /
• Density: 1.733 g/cm³
• PKA: 2.24±0.10(Predicted)
• CAS DataBase Reference: 6-Nitro-3-indazolecarboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 6-Nitro-3-indazolecarboxylic acid(857801-97-9)
• EPA Substance Registry System: 6-Nitro-3-indazolecarboxylic acid(857801-97-9)

Safety Data

• Hazardous Substances Data: 857801-97-9(Hazardous Substances Data)

Usage

General Description

6-Nitro-3-indazolecarboxylic acid is a chemical compound that belongs to the class of organic compounds known as indazoles. It is a nitro derivative of indazolecarboxylic acid. 6-Nitro-3-indazolecarboxylic acid has a nitro group at the 6-position and a carboxylic acid group at the 3-position of the indazole ring. It is used as a building block in the synthesis of various pharmaceuticals and agrochemicals. Additionally, it has shown potential biological activity in certain studies, making it an interesting target for medicinal chemistry research. Its molecular structure and properties make it a versatile compound for use in various organic reactions and chemical synthesis.

Upstream product

• 858661-74-2 3-cyano-6-nitroindazole 
• 7597-18-4 6-nitroindazole 

Downstream Products

• 1058740-77-4 1-methyl-6-nitro-1H-indazole-3-carboxylic acid 
• 1058740-88-7 methyl 1-methyl-6-nitro-1H-indazole-3-carboxylate 
• 1058740-89-8 methyl 2-methyl-6-nitro-2H-indazole-3-carboxylate 

Relevant articles and documents

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INDOLES, 1H-INDAZOLES, 1,2-BENZISOXAZOLES, AND 1,2-BENZISOTHIAZOLES, AND PREPARATION AND USES THEREOF

The present invention relates generally to the field of ligands for nicotinic acetylcholine receptors (nAChR), activation of nAChRs, and the treatment of disease conditions associated with defective or malfunctioning nicotinic acetylcholine receptors, especially of the brain. Further, this invention relates to novel compounds for example, indoles, 1H-indazoles, 1,2-benzisoxazoles, and 1,2-benzisothiazoles, which act as ligands for the α7 nAChR subtype, methods of preparing such compounds, compositions containing such compounds, and methods of use thereof.

INDAZOLES, BENZOTHIAZOLES, BENZOISOTHIAZOLES, BENZISOXAZOLES, AND PREPARATION AND USES THEREOF

The present invention relates generally to the field of ligands for nicotinic acetylcholine receptors (nACh receptors), activation of nACh receptors, and the treatment of disease conditions associated with defective or malfunctioning nicotinic acetylcholine receptors, especially of the brain. Further, this invention relates to novel compounds (e.g., indazoles and benzothiazoles), which act as ligands for the α7 nACh receptor subtype, methods of preparing such compounds, compositions containing such compounds, and methods of use thereof.