858217-21-7Relevant articles and documents
Synthesis of indole-derived allocolchicine congeners through Pd-catalyzed intramolecular C-H arylation reaction
Sitnikov, Nikolay S.,Kokisheva, Antonina S.,Fukin, Georgy K.,Neud?rfl, J?rg-Martin,Sutorius, Hannah,Prokop, Aram,Fokin, Valery V.,Schmalz, Hans-Günther,Fedorov, Alexey Yu.
, p. 6481 - 6492 (2014)
The synthesis of several new heterocyclic structural analogs of the natural antimitotic agent allocolchicine is reported. As a key step an intramolecular Pd-catalyzed C-H arylation reaction was used to close the seven-membered ring fused with two electron