858643-92-2

Basic information

• Product Name: 3-Acetyl-piperidine-1-carboxylic acid tert-butyl ester
• Synonyms: 3-Acetyl-piperidine-1-carboxylic acid tert-butyl ester;1-Boc-3-acetylpiperidine;tert-butyl 3-acetylpiperidine-1-carboxylate;1-Piperidinecarboxylic acid, 3-acetyl-, 1,1-diMethylethyl ester;3-Acetyl-1-piperidinecarboxylic acid tert-butyl ester
• CAS NO: 858643-92-2
• Molecular Formula: C₁₂H₂₁NO₃
• Molecular Weight: 227.30004
• EINECS: 200-589-5
• Mol File: 858643-92-2.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 312.4±35.0 °C(Predicted)
• Appearance: /
• Density: 1.052
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: -2.40±0.40(Predicted)
• CAS DataBase Reference: 3-Acetyl-piperidine-1-carboxylic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Acetyl-piperidine-1-carboxylic acid tert-butyl ester(858643-92-2)
• EPA Substance Registry System: 3-Acetyl-piperidine-1-carboxylic acid tert-butyl ester(858643-92-2)

Safety Data

• Hazardous Substances Data: 858643-92-2(Hazardous Substances Data)

Usage

General Description

3-Acetyl-piperidine-1-carboxylic acid tert-butyl ester is a chemical compound used in the synthesis of pharmaceuticals and organic molecules. It is a derivative of piperidine, a six-membered heterocyclic ring containing nitrogen, and contains an acetyl group and a tert-butyl ester functional group. 3-Acetyl-piperidine-1-carboxylic acid tert-butyl ester is a key intermediate in the production of various drugs and can be used as a building block in the creation of complex organic molecules. Its unique structure and reactivity make it a valuable tool in the development of new pharmaceuticals and organic compounds. Overall, 3-Acetyl-piperidine-1-carboxylic acid tert-butyl ester plays a crucial role in the field of synthetic organic chemistry and drug discovery.

Upstream product

• 75-16-1 methylmagnesium bromide 
• 189442-78-2 (±)-tert-butyl 3-(methoxy(methyl)carbamoyl)piperidine-1-carboxylate 
• 676-58-4 methylmagnesium chloride 
• 1008562-93-3 (S)-3-(methoxy-methyl-carbamoyl)-piperidine-1-carboxylic acid tert-butyl ester 
• 88495-54-9 (3S)-1-(tert-butoxycarbonyl)piperidine-3-carboxylic acid 
• 71381-75-4 N-(tert-butyloxycarbonyl)nipecotic acid 
• 148672-74-6 ethyl N-(t-butyloxycarbonyl)nipecotate 

Downstream Products

• 377780-25-1 3-(1-hydroxyethyl)piperidine-1-carboxylic acid tert-butyl ester 
• 1235439-55-0 3-(1-amino-ethyl)-piperidine-1-carboxylic acid tert-butyl ester 
• 1188264-16-5 tert-butyl 3-(1H-pyrazol-3-yl)piperidine-1-carboxylate 
• 1374353-21-5 tert-butyl 3-(1-(3-(pyridin-4-yl)-1-trityl-1H-indazol-5-yl)-1H-pyrazol-3-yl)piperidine-1-carboxylate 
• 1374351-14-0 5-(3-(1-(2-fluoro-6-methoxybenzyl)piperidin-3-yl)-1H-pyrazol-1-yl)-3-(pyridin-4-yl)-1H-indazole 

Relevant articles and documents

PYRAZOLO[1,5-A]PYRIMIDINE DERIVATIVES HAVING MULTIMODAL ACTIVITY AGAINST PAIN

The present invention relates to pyrazolopyrimidine derivatives having dual pharmacological activity towards both the α2δ subunit of the voltage-gated calcium channel and the sigma-1 (σ1) receptor, to processes of preparation of such compounds,

[1,2,4]TRIAZOLO[1,5-A]PYRIMIDINE DERIVATIVES AS PDE2 INHIBITORS

The present invention relates to novel [1,2,4]triazolo[1,5-a]pyrimidin-yl derivatives as inhibitors of phosphodiesterase 2 (PDE2). The invention is also directed to pharmaceutical compositions comprising the compounds, to processes for preparing such compounds and compositions, and to the use of such compounds and compositions for the prevention and treatment of disorders in which PDE2 is involved, such as neurological and psychiatric disorders.

PIPERIDINE AMIDES AS MODULATORS OF THE GHRELIN RECEPTOR

Compounds of formula (I) or pharmaceutically acceptable salts thereof, are useful for the treatment of diabetes and obesity.