Cas 858670-96-9,8-chloro-11-(4-fluorophenyl)-5H-dibenzo[b,e][1,4]diazepine

858670-96-9

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Basic information

Product Name: 8-chloro-11-(4-fluorophenyl)-5H-dibenzo[b,e][1,4]diazepine
Synonyms: 8-chloro-11-(4-fluorophenyl)-5H-dibenzo[b,e][1,4]diazepine
CAS NO:858670-96-9
Molecular Formula:
Molecular Weight: 322.769
EINECS: N/A
Product Categories: N/A
Mol File: 858670-96-9.mol
Article Data: 6

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: N/A
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: 8-chloro-11-(4-fluorophenyl)-5H-dibenzo[b,e][1,4]diazepine(CAS DataBase Reference)
NIST Chemistry Reference: 8-chloro-11-(4-fluorophenyl)-5H-dibenzo[b,e][1,4]diazepine(858670-96-9)
EPA Substance Registry System: 8-chloro-11-(4-fluorophenyl)-5H-dibenzo[b,e][1,4]diazepine(858670-96-9)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 858670-96-9(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 858670-96-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,5,8,6,7 and 0 respectively; the second part has 2 digits, 9 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 858670-96:
(8*8)+(7*5)+(6*8)+(5*6)+(4*7)+(3*0)+(2*9)+(1*6)=229
229 % 10 = 9
So 858670-96-9 is a valid CAS Registry Number.

858670-96-9Upstream product

858670-96-9Downstream Products

858670-96-9Relevant articles and documents

Synthesis and evaluation of dibenzothiazepines: A novel class of selective cannabinoid-1 receptor inverse agonists

Pettersson, Hanna,Bülow, Anne,Ek, Fredrik,Jensen, Jacob,Ottesen, Lars K.,Fejzic, Alma,Ma, Jian-Nong,Tredici, Andria L. Del,Currier, Erika A.,Gardell, Luis R.,Tabatabaei, Ali,Craig, Darren,McFarland, Krista,Ott, Thomas R.,Piu, Fabrice,Burstein, Ethan S.,Olsson, Roger

supporting information; experimental part, p. 1975 - 1982 (2009/12/31)

A novel class of CB1 inverse agonists was discovered. To efficiently establish structure-activity relationships (SARs), new synthetic methodologies amenable for parallel synthesis were developed. The compounds were evaluated in a mammalian cell-based func

USE OF CANNABINOID MODULATING COMPOUNDS IN COMBINATION WITH OTHER THERAPEUTIC COMPOUNDS FOR ADJUNCTIVE THERAPY

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Page/Page column 135, (2008/12/04)

The present invention relates to pharmaceutical compositions that contain a compound that modulate the activity of a cannabinoid receptor in conjunction with another therapeutic compound and uses of compounds that modulate the activity of a cannabinoid re

USE OF N-DESMETHYLCLOZAPINE AND RELATED COMPOUNDS AS DOPAMINE STABILIZING AGENTS

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Page/Page column 122, (2010/11/24)

Disclosed herein is the use of N-desmethylclozapine (NDMC) and related compounds to treat a variety of neuropsychiatric diseases including psychosis. It is shown that NDMC and related compounds are agonists or partial agonists at D2 and D3 dopamine receptors and thus may be effective as a dopamine stabilizing agent, allowing it to be used to treat or provide reduced incidence of Extrapyramidal symptoms (EPS) and/or tardive dyskinesias (TD). Also disclosed is administering NDMC and related compounds in combination with other anti-psychotic agents.

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