859129-74-1Relevant articles and documents
Synthesis, complexation, and biological activity studies of 4-aminomethyl-7,8-dihydroxy coumarines and their crown ether derivatives
Guemues, Arzu,Karadeniz, Seref,Ugras, Halil Ibrahim,Bulut, Mustafa,Cakir, Uemit,Goeren, Ahmet Ceyhan
experimental part, p. 1127 - 1133 (2010/11/03)
(Chemical Equation Presented) The article focuses synthesis of novel 4-aminomethyl-7,8-dihydroxy coumarins and their crown ether derivatives. The purified novel coumarins and their crown ether derivatives were identified by 1H NMR, 13C NMR, mass spectrometry and elemental analysis. The 1:1 binding constants of Ca2+, Mg2+, Fe2+, Zn2+, Ni2+, Cd2+, Co2+, and Mn 2+ ions at 25°C ± 0.1 with the 4-aminomethyl-7,8-dihydroxy coumarins and their crown ether derivatives estimated using extraction procedure with Inductively Coupled Plasma-Atomic Emission Spectroscopy in dichloromethane/water membrane systems. Synthesized compounds were investigated for complexation and biological activity properties. Best results in biological activity studies were observed for antioxidant activity.