859164-64-0

Basic information

• Product Name: 2-FLUORO-3-PYRIDINEMETHANAMINE
• Synonyms: RARECHEM AL BW 2476;2-FLUORO-3-PYRIDINEMETHANAMINE;(2-FLUOROPYRIDIN-3-YL)METHANAMINE;2-fluoro-3-pyridineMethanaMine dihydrochloride;(2-Fluoropyridin-3-yl)MethanaMine hydrochloride;2-Fluoro-3-pyridinemethanamine,hydrochloride;(2-Fluoropyridin-3-yl)methanamine dihydrochloride;2-fluoro-3-(aminomethyl)pyridine hydrochloride
• CAS NO: 859164-64-0
• Molecular Formula: C6H7FN2
• Molecular Weight: 126.13
• Mol File: 859164-64-0.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 225.6°C at 760 mmHg
• Flash Point: 90.2°C
• Appearance: /
• Density: 1.18g/cm³
• Vapor Pressure: 0.0858mmHg at 25°C
• Refractive Index: 1.525
• Storage Temp.: Inert atmosphere,Room Temperature
• CAS DataBase Reference: 2-FLUORO-3-PYRIDINEMETHANAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-FLUORO-3-PYRIDINEMETHANAMINE(859164-64-0)
• EPA Substance Registry System: 2-FLUORO-3-PYRIDINEMETHANAMINE(859164-64-0)

Safety Data

• Hazardous Substances Data: 859164-64-0(Hazardous Substances Data)

Usage

General Description

2-Fluoro-3-pyridinemethanamine is a chemical compound with the molecular formula C6H6FN2. It is a derivative of pyridine, a six-membered heterocyclic ring compound that contains one nitrogen atom. 2-Fluoro-3-pyridinemethanamine is characterized by the presence of a fluoro group and an amine functional group attached to the pyridine ring. It is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. The compound has potential applications in the development of drugs for the treatment of various medical conditions. 2-Fluoro-3-pyridinemethanamine is a valuable compound in organic synthesis due to its structural features and reactivity, making it an important building block in the production of diverse chemical compounds.

InChI:InChI=1S/C6H7FN2/c7-6-5(4-8)2-1-3-9-6/h1-3H,4,8H2

Upstream product

• 3939-13-7 3-cyano-2-fluoropyridine 
• 131747-55-2 2-fluoro-3-(hydroxymethyl)pyridine 
• 1034356-52-9 (2-fluoropyridin-3-yl)methyl methanesulfonate 

Relevant articles and documents

Catalytic Staudinger Reduction at Room Temperature

We report an efficient catalytic Staudinger reduction at room temperature that enables the preparation of a structurally diverse set of amines from azides in excellent yields. The reaction is based on the use of catalytic amounts of triphenylphosphine as a phosphine source and diphenyldisiloxane as a reducing agent. Our catalytic Staudinger reduction exhibits a high chemoselectivity, as exemplified by reduction of azides over other common functionalities, including nitriles, alkenes, alkynes, esters, and ketones.

CB1 MODULATOR COMPOUNDS

Novel compounds of structural formula (I) are disclosed. As modulators of the Cannabinoid-1 (CB1) receptor, these compounds are useful in the treatment, prevention and suppression of diseases mediated by the CB1 receptor. As such, compounds of the present invention are useful as in the treatment, prevention and suppression of psychosis, memory deficits, cognitive disorders, migraine, neuropathy, neuro-inflammatory disorders (e.g., multiple sclerosis, Guillain-Barre syndrome and the inflammatory sequelae of viral encephalitis), cerebral vascular accidents, head trauma, anxiety disorders, stress, epilepsy, Parkinson's disease, and schizophrenia. The compounds are also useful for the treatment of substance abuse disorders, particularly to opiates, alcohol, and nicotine. The compounds are also useful for the treatment of obesity or eating disorders associated with excessive food intake and complications associated therewith.