859213-29-9

Basic information

• Product Name: (S)-1-(benzyloxycarbonyl)-3-(N,N-diethylamino)pyrrolidine
• Synonyms: (S)-1-(benzyloxycarbonyl)-3-(N,N-diethylamino)pyrrolidine
• CAS NO: 859213-29-9
• Molecular Weight: 276.379
• Mol File: 859213-29-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-1-(benzyloxycarbonyl)-3-(N,N-diethylamino)pyrrolidine(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-1-(benzyloxycarbonyl)-3-(N,N-diethylamino)pyrrolidine(859213-29-9)
• EPA Substance Registry System: (S)-1-(benzyloxycarbonyl)-3-(N,N-diethylamino)pyrrolidine(859213-29-9)

Safety Data

• Hazardous Substances Data: 859213-29-9(Hazardous Substances Data)

Upstream product

• 75-03-6 ethyl iodide 
• 122536-72-5 (S)-3-amino-1-pyrrolidinecarboxylic acid phenylmethyl ester 

Downstream Products

• 1181083-20-4 (S)-3-(N,N-diethylamino)pyrrolidine dichloride 

Relevant articles and documents

AMIDE DERIVATIVE AND MEDICINE

The present invention is directed to an amide derivative having excellent BCR-ABL tyrosine kinase inhibitory activity, or a salt thereof. The present invention provides an amide derivative represented by the following general formula [1]: (wherein R1 represents -CH2-R11, etc.; R2 represents alkyl, halogen, haloalkyl, etc.; R3 represents hydrogen, etc.; Het1 represents a group of the formula [6] as above, etc.; and Het2 represents pyrimidinyl, etc.), or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition comprising the same as an active ingredient. The compound of the present invention is useful as a BCR-ABL tyrosine kinase inhibitor.