85929-74-4

Basic information

• Product Name: 3-Formyl-2,2,5,5-tetramethyl-thiazolidine-4-carboxylic acid N'-phenyl-hydrazide
• CAS NO: 85929-74-4
• Molecular Weight: 307.417
• Mol File: 85929-74-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-Formyl-2,2,5,5-tetramethyl-thiazolidine-4-carboxylic acid N'-phenyl-hydrazide(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Formyl-2,2,5,5-tetramethyl-thiazolidine-4-carboxylic acid N'-phenyl-hydrazide(85929-74-4)
• EPA Substance Registry System: 3-Formyl-2,2,5,5-tetramethyl-thiazolidine-4-carboxylic acid N'-phenyl-hydrazide(85929-74-4)

Safety Data

• Hazardous Substances Data: 85929-74-4(Hazardous Substances Data)

Upstream product

• 100-63-0 phenylhydrazine 
• 55234-12-3 D-(+)-3-formyl-2,2,5,5-tetramethyl-thiazolidine-4-carboxylic acid 

Relevant articles and documents

On the Reactivity of Penicillamine and its Derivatives. Joint Reaction of Elementary Sulfur and Gaseous Ammonia with Ketones, 97

DL-penicillamine-hydrochloride was condensed with various aldehydes (1 - 22) and ketones (23 - 28) to the corresponding 5,5-dimethyl-thiazolidine-4-carboxylic acid hydrochlorides and the free bases respectively.Their methylesters were obtained with diazomethane or methanol (29 - 35).Various 5,5-dimethyl-thiazolidine-4-carboxylic acids were formylated in position 3 (36 - 39).The reactivity of the carboxylic group was studied for 3-formyl-2,2,5,5-tetramethyl-thiazolidine-4-carboxylic acid.Substituted N-penicillaminamides were obtained for the first time (40 - 53).Also some S-alkylated penicillamines were prepared (54 - 60).By diazotation of 2,2,5,5-tetramethyl-thiazolidine-4-carbonamide or of penicillaminamide itself, 2-carbamyl-3,3-dimethyl-ethylene-sulfide was obatined. - Keywords: 3-Formyl-2,2,5,5-tetramethyl-thiazolidine-carboxylic acid amides; N-Formyl-5,5-dimethyl-thiazolidine-4-carboxylic acids; S-Alkylpenicillamines