859788-87-7Relevant articles and documents
Synthesis and phosphodiesterase 5 inhibitory activity of novel pyrido[1,2-e]purin-4(3H)-one derivatives
Xia, Guangxin,Li, Jianfeng,Peng, Aiming,Lai, Shunan,Zhang, Shujun,Shen, Jingshan,Liu, Zhonghua,Chen, Xinjian,Ji, Ruyun
, p. 2790 - 2794 (2007/10/03)
Synthesis and primary SAR of a novel series of 2-phenylpyrido[1,2-e]purin- 4(3H)-one derivatives with piperazinyl sulfonamide substituents were described herein. As potential PDE5 inhibitors for erectile dysfunction (ED) treatment, representative compound