860019-36-9Relevant articles and documents
2-Phenylimidazo[1,2-b]pyridazine derivatives highly active against Haemonchus contortus
Ali, Abdelselam,Cablewski, Teresa,Francis, Craig L.,Ganguly, Ashit K.,Sargent, Roger M.,Sawutz, David G.,Winzenberg, Kevin N.
supporting information; experimental part, p. 4160 - 4163 (2011/08/10)
A series of 2-phenylimidazo[1,2-b]pyridazine derivatives were synthesized and evaluated for their in vitro anthelmintic activity against Haemonchus contortus. The most active compounds had in vitro LD99 values of 30 nM, which is comparable to that of the benchmark commercial nematocide, Ivermectin.