860032-57-1Relevant articles and documents
Discovery of TD-4306, a long-acting β2-agonist for the treatment of asthma and COPD
McKinnell, R. Murray,Klein, Uwe,Linsell, Martin S.,Moran, Edmund J.,Nodwell, Matthew B.,Pfeiffer, Juergen W.,Thomas, G. Roger,Yu, Cecile,Jacobsen, John R.
, p. 2871 - 2876 (2014/06/10)
A multivalent approach focused on amine-based secondary binding groups was applied to the discovery of long-acting inhaled β2-agonists. Addition of amine moieties to the neutral secondary binding group of an existing β2-agonist serie