860033-71-2Relevant articles and documents
Design, synthesis, and evaluation of proline based melanocortin receptor ligands
Tian, Xinrong,Field, Timothy,Mazur, Adam W.,Ebetino, Frank H.,Wos, John A.,Crossdoersen, Doreen,Pinney, Beth B.,Sheldon, Russell J.
, p. 2819 - 2823 (2007/10/03)
A series of proline based melanocortin ligands has been developed on the basis of initial piperazine leads by using a more conformationally rigid scaffold. A number of these novel ligands showed significant binding affinity for MC3 and MC4 receptors.