86048-50-2

Basic information

• Product Name: N-((1H-indol-3-yl)(phenyl)methyl)aniline
• Synonyms: N-((1H-indol-3-yl)(phenyl)methyl)aniline
• CAS NO: 86048-50-2
• Molecular Weight: 298.387
• Mol File: 86048-50-2.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: N-((1H-indol-3-yl)(phenyl)methyl)aniline(CAS DataBase Reference)
• NIST Chemistry Reference: N-((1H-indol-3-yl)(phenyl)methyl)aniline(86048-50-2)
• EPA Substance Registry System: N-((1H-indol-3-yl)(phenyl)methyl)aniline(86048-50-2)

Safety Data

• Hazardous Substances Data: 86048-50-2(Hazardous Substances Data)

Upstream product

• 120-72-9 indole 
• 538-51-2 benzylidene phenylamine 
• 100-52-7 benzaldehyde 
• 62-53-3 aniline 
• 98-95-3 nitrobenzene 
• 1750-36-3 (E)-N-benzylidenebenzenamine 

Downstream Products

• 27152-07-4 2,8-diphenyl-1,2,3,8-tetrahydroindolo[2,3-b]carbazole 

Relevant articles and documents

Lanthanide triflates catalyzed reactions of imines with indole in protic media

Lanthanide triflates Ln(OTf)3 were found to catalyze the electrophilic substitution reactions of indole with a variety of imines in protic media, affording predominately secondary indolyl amines as well as bisindolyl methanes as by-products.

Natural Products for Drug Discovery: Discovery of Gramines as Novel Agents against a Plant Virus

Plant viral diseases seriously affect crop yield and quality. The natural product gramine (1) and its simple structural analogues 2-35 were synthesized from indoles, amines, and aldehydes in one step. The antiviral effects of these alkaloids were evaluated systematically. Most of these compounds were found to have higher antiviral effects than commercial ribavirin for the first time. Especially compounds 22, 30, and 31 exhibited significantly higher effects than ningnanmycin, thereby emerging as novel antiviral leads for further optimization. The preliminary implementation indicated that these compounds likely inhibit the assembly of tobacco mosaic virus (TMV) by cross-linking TMV capsid protein. Gramine analogues were also found to have broad-spectrum fungicidal effects. Although gramine has been reported to have influence on germination and development of Erysiphe graminis, these compounds displayed no fungicidal effects against Blumeria graminis f. sp. tritici on wheat in our test. Some of these compounds also exhibited certain insecticidal activities.

Dy(OTf)3 in ionic liquid: An efficient catalytic system for reactions of indole with aldehydes/ketones or imines

Dy(OTf)3 immobilized in ionic liquids was found to be an efficient catalytic system for the reactions of indole with aldehydes/ketones or imines. Enhanced activity was observed. The use of ionic liquids as the reaction media allows facile separ