86061-05-4

Basic information

• Product Name: N-FMOC-L-SERINE PENTAFLUOROPHENYL ESTER)
• Synonyms: N-FMOC-L-SERINE PENTAFLUOROPHENYL ESTER);N-(9-fluorenylmethoxycarbonyl)-L-serine pentafluorophenyl
• CAS NO: 86061-05-4
• Molecular Formula: C₂₄H₁₆F₅NO₅
• Molecular Weight: 493.38
• Mol File: 86061-05-4.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N-FMOC-L-SERINE PENTAFLUOROPHENYL ESTER)(CAS DataBase Reference)
• NIST Chemistry Reference: N-FMOC-L-SERINE PENTAFLUOROPHENYL ESTER)(86061-05-4)
• EPA Substance Registry System: N-FMOC-L-SERINE PENTAFLUOROPHENYL ESTER)(86061-05-4)

Safety Data

• Hazardous Substances Data: 86061-05-4(Hazardous Substances Data)

Upstream product

• 771-61-9 2,3,4,5,6-pentafluorophenol 
• 73724-45-5 N-(9H-fluoren-9-ylmethoxycarbonyl)-L-serine 
• 105751-13-1 O-tert-butyl-N^α-(fluoren-9-ylmethoxycarbonyl)-L-serine pentafluorophenyl ester 

Downstream Products

• 149704-74-5 N^α-(Fluoren-9-ylmethoxycarbonyl)-O-(2,3,4,6-tetra-O-benzoyl-β-D-glucopyranosyl)-L-serine pentafluorophenyl ester 
• 141462-11-5 N^α-(9H-fluoren-9-yl)methoxycarbonyl-O-(3,4,6-tri-O-acetyl-2-azido-2-deoxy-α-D-galactopyranosyl)-L-serine pentafluorophenyl ester 
• 129398-80-7 Fmoc--Ser-O-Pfp 
• 160410-55-9 N^α-(fluoren-9-ylmethoxycarbonyl)-O-(3,4,6-tri-O-acetyl-2-allyloxycarbonylamino-2-deoxy-β-D-glucopyranosyl)-L-serine pentafluorophenyl ester 
• 143537-80-8 N^α-(fluoren-9-ylmethoxycarbonyl)-O-<3,4,6-tri-O-acetyl-2-O-(2,3,4,6-tetra-O-acetyl-α-D-mannopyranosyl)-α-D-mannopyranosyl>-L-serine pentafluorophenyl ester 
• 162894-84-0 N^α-(fluoren-9-ylmethoxycarbonyl)-O-(3,4,6-tri-O-acetyl-2-deoxy-2-dithiasuccinimido-β-D-glucopyranosyl)-L-serine pentafluorophenyl ester 
• 243469-45-6 N^α-(9-Fluorenylmethoxycarbonyl)-3-O-(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-L-serine pentafluorophenyl ester 
• 174004-28-5 (S)-3-[(2R,3R,4R,5S,6R)-4,5-Diacetoxy-6-acetoxymethyl-3-(2,2,2-trichloro-ethoxycarbonylamino)-tetrahydro-pyran-2-yloxy]-2-(9H-fluoren-9-ylmethoxycarbonylamino)-propionic acid pentafluorophenyl ester 

Relevant articles and documents

Syntheses of TN building blocks Nα-(9- fluorenylmethoxycarbonyl)-O-(3,4,6-tri-O-acetyl-2-azido-2-deoxy-α-D- galactopyranosyl)-L-serine/L-threonine pentafluorophenyl esters: Comparison of protocols and elucidation of side reactions

TN antigen building blocks Nα-(9- fluorenylmethoxycarbonyl)-O-(3,4,6-tri-O-acetyl-2-azido-2-deoxy-α-d- galactopyranosyl)-l-serine/l-threonine pentafluorophenyl ester [Fmoc-l-Ser/l-Thr(Ac3-α-d-GalN3)-OPfp, 13/14]

9-Fluorenylmethyl Pentafluorophenyl Carbonate as a Useful Reagent for the Preparation of N-9-Fluorenylmethyloxycarbonylamino Acids and their Pentafluorophenyl Esters

9-Fluorenylmethyl pentafluorophenyl carbonate is a useful reagent for the efficient, side reaction-free introduction of N-9-fluorenylmethyloxycarbonyl protecting group into amino acids and for the subsequent preparation of their pentafluorophenyl esters.Some new compounds of both types are described.