860617-71-6Relevant articles and documents
Novel progesterone receptor modulators: 4-Aryl-phenylsulfonamides
McComas, Casey,Cohen, Jeffrey,Huselton, Christine,Marella, Michael,Melenski, Edward,Mugford, Cheryl,Slayden, Ov,Winneker, Richard,Wrobel, Jay,Yudt, Matthew R.,Fensome, Andrew
, p. 7119 - 7122 (2013/01/15)
We have developed a new series of progesterone receptor modulators based upon the 4-aryl-phenylsulfonamide. Initial work in the series afforded potent compounds with good properties, however an advanced intermediate proved to be genotoxic in a non-GLP Ame
Use of progesterone receptor modulators
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Page/Page column 15, (2010/11/25)
The use of compounds of formula I, or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R4, R5, R6 and R7, are as defined herein, for contraception, hormone replace
Progesterone receptor modulators comprising pyrrole-oxindole derivatives and uses thereof
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Page/Page column 8, (2010/02/15)
Pyrrole-oxindole derivatives useful as progesterone receptor antagonists are provided. Pharmaceutical compositions containing these derivatives are described, as is the use thereof in contraception and hormone-related conditions.