860624-96-0 Usage
General Description
Methyl 5-phenyl-1H-indole-7-carboxylate is an organic compound belonging to the class of carboxylic acid esters. It is derived from indole, a heterocyclic compound commonly found in various natural products and pharmaceuticals. Methyl 5-phenyl-1H-indole-7-carboxylate has a molecular structure consisting of a methyl group, a phenyl group, and an indole ring with a carboxylate functional group attached at the 7th position. methyl 5-phenyl-1H-indole-7-carboxylate has potential applications in the fields of organic synthesis, medicinal chemistry, and pharmaceutical research due to its unique structure and properties.
Check Digit Verification of cas no
The CAS Registry Mumber 860624-96-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,6,0,6,2 and 4 respectively; the second part has 2 digits, 9 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 860624-96:
(8*8)+(7*6)+(6*0)+(5*6)+(4*2)+(3*4)+(2*9)+(1*6)=180
180 % 10 = 0
So 860624-96-0 is a valid CAS Registry Number.
860624-96-0Relevant articles and documents
3,5-Disubstituted-indole-7-carboxamides as IKKβ Inhibitors: Optimization of Oral Activity via the C3 Substituent
Kerns, Jeffrey K.,Busch-Petersen, Jakob,Fu, Wei,Boehm, Jeffrey C.,Nie, Hong,Muratore, Michael,Bullion, Ann,Lin, Guoliang,Li, Huijie,Davis, Roderick,Lin, Xichen,Lakdawala, Ami S.,Cousins, Rick,Field, Rita,Payne, Jeremy,Miller, David D.,Bamborough, Paul,Christopher, John A.,Baldwin, Ian,Osborn, Ruth R.,Yonchuk, John,Webb, Edward,Rumsey, William L.
supporting information, p. 1164 - 1169 (2018/11/23)
IκB kinase β (IKKβ or IKK2) is a key regulator of nuclear factor kappa B (NF-κB) and has received attention as a therapeutic target. Herein we report on the optimization of a series of 3,5-disubstituted-indole-7-carboxamides for oral activity. In doing so