860684-36-2Relevant articles and documents
Brain Microdialysis Coupled to LC-MS/MS Revealed That CVT-10216, a Selective Inhibitor of Aldehyde Dehydrogenase 2, Alters the Neurochemical and Behavioral Effects of Methamphetamine
Kim, Seungju,Jang, Eun Young,Song, Sang-Hoon,Kim, Ji Sun,Ryu, In Soo,Jeong, Chul-Ho,Lee, Sooyeun
, p. 1552 - 1562 (2021/05/10)
Methamphetamine (MA), a potent central nervous system stimulant, mainly affects the brain dopaminergic and serotoninergic systems. Monoamine oxidase, catechol-O-methyltransferase, and aldehyde dehydrogenase 2 (ALDH2) are important enzymes in the metabolis